Drug & Polymer Properties
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Everolimus targets which stage of the restenosis cascade?
Inflammation (anti-inflammatory agents) & Proliferation (anti-proliferative agents)
Paclitaxel targets which stage of restenosis?
Proliferation (anti-proliferative agents)
Everlimus is the active agent in what drug?
Certican (Novartis) - used for prevention of rejection of heart, kidney & lung transplants
Why Everlimus is the ideal drug
- Proven clinical performance: efficacious and safe
- Preferred Mechanism of Action: cytostatic and non-inflammatory
- Wide therapeutic window: excellent tissue compatibility & effective at multiple doses with minimal toxicity
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