Drug & Polymer Properties

Card Set Information

Author:
kellytange
ID:
160382
Filename:
Drug & Polymer Properties
Updated:
2012-06-28 11:03:05
Tags:
Drug Polymer
Folders:

Description:
The Properties of the ideal drug and polymer
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  1. Restenosis Cascade
    • Thrombosis
    • Inflammation
    • Proliferation
    • Migration
    • Healing
  2. Everolimus targets which stage of the restenosis cascade?
    Inflammation (anti-inflammatory agents) & Proliferation (anti-proliferative agents)
  3. Paclitaxel targets which stage of restenosis?
    Proliferation (anti-proliferative agents)
  4. Everlimus is the active agent in what drug?
    Certican (Novartis) - used for prevention of rejection of heart, kidney & lung transplants
  5. Why Everlimus is the ideal drug
    • Proven clinical performance: efficacious and safe
    • Preferred Mechanism of Action: cytostatic and non-inflammatory
    • Wide therapeutic window: excellent tissue compatibility & effective at multiple doses with minimal toxicity

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