psychopharmacology

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Author:
mslilybee
ID:
160603
Filename:
psychopharmacology
Updated:
2012-07-23 00:28:20
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psychiatry
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psych cards
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  1. Treatment of panic disorders
    SSRIs
  2. Valproic acid (Divalproex)
    N/V, sedation, weigth gain, transitory hair loss, transient increase in LFTs
  3. donepezil
    • cholinesterase inhibitor
    • used for mild to moderate Alzheimer's
  4. rivastigmine
    • cholinesterase inhibitor
    • mild to mod Alzheimer's
  5. galantamine
    • cholinesterase inhibitor
    • mild to mod Alzheimer's
  6. clozapine
    • *atypical antipsychotic
    • *agranulocytosis
    • *hypersalivation that can cause aspiration despite anticholinergic activity
    • *myocarditis
    • only antipsychotic shown to decrease risk of suicide
  7. Chlorpromazine
    • Thorazine
    • low-potency typical antipsychotic
    • orthostatic hypotension
    • bluish skin discoloration
    • photosensitivity
    • can treat N/V and intractable hiccups
  8. Thioridazine (Mellaril)
    retinitis pigmentosa
  9. Loxapine (Loxitaine
    • higher risk of seizure
    • metabolite is an antidepressant
    • mid-potency typical neurleptic
  10. trifluoperazine (Stelazine)
    • mid-potency typical neurleptic
    • can reduce anxiety
  11. Perphenazine
    midpotency neuroleptic
  12. Haloperidol (Haldol)
    • high potency neuroleptic
    • used for Tourette d/o
  13. Fluphenazine
    *high potency typical neuroleptic
  14. Pimozide
    • high potency typical neuroleptic
    • associated with heart block, ventricular tachycardia, and other cardiac effects
  15. Risperidone
    • atypical antipsychotic
    • *prolactinemia
    • *orthostatic hypotension and reflex tachycardia
  16. Quetiapine (Seroquel)
    • atypical antipsychotic
    • *sedation
    • *orthostatic hypotension
  17. Olanzapine
    • atypical antipsychotic
    • weight gain
  18. Ziprasidone (Geodon)
    • atypical antipsychotic
    • less likely to cause weight gain
  19. Aripiprazole (Abilify)
    • atypical antipsychotic
    • *unique mechanism of partial D2 agonism
    • *can be more activating (akathisia) and less sedating
    • *less potential for weight gain
  20. Paliperidone (Invega)
    • newer atypical antipsychotic
    • *metabolite of risperidone
  21. sustenna
    long-acting rejectable form of paliperidone
  22. asenapine
    • (Saphris)
    • *atypical antipsychotic
  23. Iloperidone (Fanapt)
    atypical antipsychotic
  24. SE of atypical antipsychotics in general
    • QTc prolongation
    • liver fxn-monitor LFTs
    • metabolic syndrome
    • hyperglycemia
    • some anti-HAM effects
  25. QTc prolongation culprits
    • atypical antipsychotics
    • TCAs(general widening of QRS, QT, and PR intervals avoid in patients with preexisting cardiac disese)
  26. flumazenil
    • tx for benzo overdose
    • can precipatate seizures in those with pre-existing seizure d/o
  27. Ritalin
    • SE
    • insomnia is best known
    • others- GI distress, HA, decrease appetite, emergence of tics
  28. Treatment for Tourette d/o
    Haloperidol
  29. Treatment for narcolepsy
    • amphetamines
    • if cataplexy is present SSRIs and TCAs or antidepressants in general
  30. P450 inducers
    • Barbituates
    • Carbamazepine
    • Griseofulvin
    • Phenytoin
    • Quinidine
    • Rifampin (rev up enzyme)
    • St. John's Wort
  31. P450 inhibitors
    • Protease inhibitors
    • Isoniazid
    • Cimetidine
    • Ketaconazole
    • Erythromycin
    • Grapefruit Juice
    • Sulfonamides
  32. Treatment for PTSD
    many different treatments but clonidine and beta blockers particularly good for hyperarousal
  33. amantidine
    • dopaminergic via decrease reuptake of dopamine and other stuff
    • used for parkinsons
    • used for neuroleptic malignant syndrome
    • (could also use bromocriptine or dantrolene)
  34. tx for NMS
    supportive care then consider dantrolene or maybe amatidine or bromocriptine (dopaminergic agents)
  35. Depot versions of antipsychotics
    • Fluphenazine deconate (2x/month)
    • Haloperidol deconate (2x/month)
    • Risperidone depot (2x/month)
    • Paliperidone depot (1x/month)

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