- → Decrease afterload
- → Not used alone because of reflex tachycardia
- → Act on arteries inc blood flow to brain & kidneys, reflex tachy can result from the vasodilation and accompanying dec BP, so beta blockers are jointly Rx to dec HR.
- → Apresoline
- → Nipride
- Hypertensive emergency - Nipride (arterial and venous) & diazoxide (arterial only)
Stop drug if: Thiocyanate toxicity: hypotension, tinnitus, dyspnea, blurred vision, metabolic acidosis
Cautious lowering to avoid stroke, MI, acute renal failure!!
→ Nipride decomposes in light; container must be wrapped in Al foil. Good for 24 hr. Discard is red or blue. Can cause cyanide toxicity.