Card Set Information
USMLE Stuff to memorize
In Mononucleosis you should find hyperplasia of what part of the lymph node and of the spleen?
Paracortex of LNs and periarterial lymphatic sheath of the white pulp of spleen.
EBV infects these three main areas/organs:
Oropharynx, liver, B-cells
Infectious Mononucleosis is caused by which two bugs?
EBV and sometimes CMV
What test do you use for mononucleosis screening and then confirmation if it is due to EBV?
Monospot test--heterophile antigen pos for IgM (lyse sheep RBCs) and then EBV viral capside antibodies
What marker is found in ALL?
TdT, a marker of pre-T and pre-B cells
This ALL translocation is associated with a better prognosis:
t (12, 21)
This cell surface markers are associated with B-ALL:
CD 10, 19, 20
These cell surface markers are associated with T-ALL and seen where in teens?
CD2-8, thymic mass in teens--lymphoma
ALL needs chemotherapy prophylaxis to which areas?
Scrotum and CSF
This leukemia affects Down's kids older than 5:
This leukemia affects Down's kids younger than 5:
Acute Megakaryocytosis Leukemia
This disease is associated with Auer Rods, which are crystal aggregates of MPO
This leukemia is common in adults, gen 55+, and the M3 form responds well to all-trans retinoic acid due to it's binding to dysrupted RAR-receptors and inducing the maturation of certain cells:
Translocation associated with AML: