Dyslipidemia

Card Set Information

Author:
adguvetis
ID:
162034
Filename:
Dyslipidemia
Updated:
2012-07-10 22:01:33
Tags:
Pharmacy
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Description:
NAPLEX Study Cards
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  1. Friedewald Equation for calculating LDL
    LDL = CH - HDL - (TG/5) (cannot use if TG > 400 mg/dL)
  2. CHD and CHD Risk Equivalents
    • Clinical CHD- Hx of MI, angina, coronary procedures
    • Symptomatic carotid artery disease (TIA, stroke)
    • Peripheral arterial disease (PAD)
    • Abdominal aortic aneurysm
    • Diabetes
    • Multiple risk factors that confer >20% CHD risk at 10 years 
  3. Major risk factors for CHD
    • Age - Men > 45 y/o, Women > 55 y/o
    • Cigarette smoking
    • HTN - BP > 140/90 mmHg or on antihypertensives
    • Family Hx of premature CHD - < 55 y/o in 1st degree male relative, <65 y/o in 1st degree female relative

    Negative risk factor - HDL > 60 mg/dL 
  4. Primary drugs to lower LDL
    Statins
  5. Statins safe for nursing mothers
    Crestor, Lipitor, Livalo, Pravachol
  6. May cause upper RTIs
    Ezetimibe
  7. Must separate all other drugs by 1 hour before or 4-6 hours after
    • Cholestyramine (Questran)
    • Colestipol (Colestid) 
  8. Must take 4 hours prior to Welchol
    • Phenytoin
    • Levothyroxine
    • Glyburide
    • Oral contraceptives 
  9. Simcor
    Niaspan + simvastatin
  10. Causes flushing/itching
    Niacin
  11. To counteract flushing with Niacin
    Pretreat with 325mg uncoated ASA or 200mg Ibuprofen 30 minutes before dose
  12. Best for decreasing triglycerides
    • Fibrates
    • Niacin
    • Lovaza 

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