Top 200 APAP w/Codeine-Allopurinol

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  1. What schedule is Acetaminophen with Codeine?
    C-III (but the elixer is C-V)
  2. What are two brand names for Acetaminophen with Codeine?
    Tylenol or Phenaphen with Codeine
  3. When should the dosage range for Acetaminophen with Codeine be exceeded?
    • Patients with more severe pain
    • Tolerance to narcotic analgesics exists
  4. What category of drug is Acetaminophen with Codeine?
    Opiod Analgesic
  5. What is the MOA of Acetaminophen?
    • Inhibits prostaglandin synthesis in the CNS
    • Peripherally blocks pain impulse generation
  6. What is the MOA of Codeine?
    Produces analgesia centrally though action on the central opoiate receptors
  7. How is Acetaminophen with Codeine excreted?
    Through the urine
  8. Drug Interactions of Acetaminophen with Codeine
    What drugs produce additive CNS depression?
    • CNS depressants
    • Alcohol
  9. Drug Interactions of Acetaminophen with Codeine
    What drugs increase the risk of heptotoxicity?
    • Hydantoins
    • Sulfinpyrazone
  10. What pregnancy category is Acetaminophen with Codeine?
    Pregnancy Category C
  11. What are some of the Adverse effects associate with Acetaminophen with Codeine?
    • Dizziness
    • Drowsiness
    • Constipation
    • Nausea
    • Vomiting
  12. What types of patients would you use caution when using Acetaminophen with Codeine?
    • Increase Intracranial pressure
    • Head injury
    • Hepatic/renal impairment
    • Addison's disease
    • Hypothyroidism
    • BPH/urethral stricture
    • Acute abdominal conditions
  13. What should be done if a dose of Acetaminophen with Codeine is missed?
    Skip it and return to normal dosing schedule
  14. Should you take Acetaminophen with Codeine with food or milk?
    Yes, to avoid GI upset
  15. What forms does Acetaminophen and Codeine come in?
    • Tablets
    • Elixir
  16. What is the brand name for Acyclovir?
  17. What forms does Acyclovir come in?
    • Capsules
    • Tablets
    • Ointment
    • Cream
    • Suspension
    • Powder for injection
  18. What is the MOA of Acyclovir?
    ?! FILL IN!!!
  19. What category of drugs does Acyclovir fall under?
  20. How long does it take for Acyclovir to reach steady state plasma levels?
    2 days
  21. Drug Interactions of Acyclovir
    What drug may decrease elimination of Acyclovir?
  22. What is Acyclovir used for treating?
    • Genital herpes (acute and recurrent)
    • Chickenpox
    • Shingles
    • HSV-1 and HSV-2
  23. Does Acyclovir require renal adjustment?
  24. What precaution should patients with herpes on Acyclovir be told?
    • Avoid sexual intercouse while visible lesions exist
    • Medication does eliminate virus or cure herpes
  25. What pregnancy category is Acyclovir?
  26. What are some of the adverse effects of Acyclovir?
    • Nausea, vomiting (tablets, capsules)
    • stinging, burning, pruritus (ointment)
    • phlebitis, inflmation, transient creatininte elevations, rash, hives (injection)
  27. What should be done if a dose of Acyclovir is missed?
    Take as soon as possible but don't double dose
  28. T/F Acyclovir requires plenty of fluid intake?
  29. What category of drug is Albuterol sulfate?
  30. What are three brand names for Albuterol Sulfate?
    • Proventil
    • Ventolin
    • Proair
  31. What forms does Albuterol Sulfate come in?
    HFA Inhaler and Solution for inhalation
  32. What is Albuteral Sulfate used for?
    • Relief of bronchospasm in patients with reversible obstructive airway disease
    • Prevention of expercise induced bronchospasm
    • Maintenance to prevent exacerbation of bronchospasms
  33. What is the MOA of Albuteral Sulfate?
    Stimulates adenyl cyclase, the enzyme that catlyzes the formation of c-AMP from ATP.  This relaxes the bronchial, uterine, and vascular smooth muscle by stimulating beta-2-adrenergic receptors
  34. How is Albuteral Sulfate excreted?
    Through the urine
  35. Is Albuteral Sulfate systemically absorbed?
    No, very minimally
  36. What drugs may increase the toxicity of Albuteral Sulfate?
    • Sympathomimetics
    • Tricyclic Antidepressants
    • Monoamine Oxidase Inhibitors
  37. What may Albuteral Sulfate cause when used with nonpotassium sparing diuretics?
    • Worsen hypokalemia
    • Worsen ECG changes
  38. Albuteral Sulfate has what effect on digoxin levels?
    May decrease serum digoxin
  39. What pregnancy category is Albuteral Sulfate?
  40. What types of patients should use Albuteral sulfate with caution?
    • Cardiovascular disorders
    • Hypertension
    • Hyperthyroidsim
    • DM
    • Nursing or Pregnant
  41. What are some adverse effects of Albuteral Sulfate?
    • Nausea
    • vomiting
    • nervousness
    • headache
    • insomnia
    • tremor
    • dizziness
    • hypertension
    • tachycardia
    • palpitation
  42. How should the mouthpiece for an albuterol inhaler be cleaned?
    Weekly, remove canister, run warm water through it for 30 seconds, air dry thoroughly
  43. What is the brand name for Alendronate Sodium?
  44. What category of agent is Alendronate Sodium?
    Osteoporosis agent
  45. What dosage forbs does Alendronate Sodium come in?
    Tablets and oral solution
  46. What is Alendronate sodium used to treat?
    • Osteoporosis in postmenopausal women
    • Prevention or osteoporosis
    • Increase bone mass
    • Paget's disease
  47. How should Alendronate sodium be taken?
    With plain water, after waking, do not eat or lie for at least 30 minutes after
  48. What is the MOA of Alendronate sodium?
    Inhibits osteoclast activity, encourages new bone formation.  Not pharmacologically active
  49. Excretion of Alendronate sodium?
    Urine unmetabolized
  50. Drug Interactions with Alendronate sodium
    Decrease absorption?
    • Antacids
    • Calcium
  51. Drug Interactions with Alendronate sodium
    GI adverse effects?
  52. Pregnancy category of Alendronate sodium?
  53. Contraindicated patients for Alendronate sodium?
    • Can't sit upright for 30 minutes
    • Hypocalcemia
    • Delayed esophageal empting
    • Creatine clearance less than 35
  54. Adverse effects of Alendronate Sodium?
    • Abdominal pain
    • constipation
    • diarrhea
    • flatulence
    • musculoskeletal pain
  55. Should Alendronate sodium be double dosed?
    No, if dose is missed wait until next scheduled time
  56. What category of drug is Allopurinol?
    Agent for gout
  57. What is the brand name for Allopurinol?
  58. What forms is Allopurinol available in?
    • Tablets
    • Solution for injection
  59. What is Allopurinol indicated for?
    • Treatment of gout, uric acid nephropathy
    • prevention of uric acid nephropathy
    • Prevention of gouty arthritis flare ups
    • Secondary hyper uricemia
    • Treatment of recurrent calcium oxalate stones
  60. How does Allopurinol work?
    Competitively inhibits xanthine oxidase so hypoxanthine cannot be converted touric acid
  61. Drug Interactions with Allopurinol?
    Allopurinol can cause what type of rash?
    ampicillin induced
  62. Drug Interactions with Allopurinol
    What drugs does Allopurinol increase the toxic effects of?
    • Thiopurines (mercaptopurine and azathiopurine)
    • Chlorpropamide
  63. Pregnancy catergory of Allopurinol?
  64. Adverse effects of allopurinol?
    • Drowsiness
    • diarrhea
    • nausea
    • vomiting
    • abdominal pain
    • rash
  65. Caution should be used in what type of patient when using Allopurinol?
    Renally impaired
  66. How much urine output should a patient using allopurinol have?
    At least 2 liters a day
  67. Does Allopurinol work instantaneously?
    No, may take one or more weeks.
  68. What beverage should be avoided while on Allopurinol?
  69. What should be done if a dose of Allopurinol is missed?
    Skip it and take next regularly scheduled dose
  70. Should allopurinol be taken on an empty stomach?
    No, with milk or food is better to avoid GI upset
Card Set:
Top 200 APAP w/Codeine-Allopurinol
2012-07-16 20:56:07
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