Pathology - Lecture 4

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Anonymous
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163482
Filename:
Pathology - Lecture 4
Updated:
2012-07-22 09:46:20
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McGriff Summer 2012
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Lecture 4 - July 19
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  1. What are the 2 main components of adaptive immunity?
    • Humoral
    • Cellular
  2. How is adaptive immunity activated?
    Through antigen presentation
  3. What are the 3 parts of an antibody's structure?
    • Antigen-binding fragment, Fab - variable and constant regions
    • Crystalline fragment, Fc
    • Polypeptide chains - 2 light chains, 2 heavy chains
  4. Where is the B-cell receptor complex located? What does it consist of? What does it do?
    • Located on the surface of B-cells
    • Consists of antigen-recognition molecules and accessory intracellular-signaling molecules
    • Activates B-cells to become plasma cells
  5. What is the T-cell receptor complex made of?
    • Antibody-like transmembrane proteinĀ 
    • Accessory proteins for intracelllar signaling (CD3)
  6. Where does clonal diversity occur?
    Primary lymphoid organs

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