Thyroid, Adrenal, Misc Endocrine Drugs

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Author:
evelngo
ID:
164460
Filename:
Thyroid, Adrenal, Misc Endocrine Drugs
Updated:
2012-07-30 16:58:49
Tags:
Endocrine
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Thyroid, Adrenal, Misc Endocrine Drugs
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  1. When and how often should you take thyroid hormones?
    ONCE daily 30 minutes before breakfast
  2. Do NOT take antacids, calcium, or iron supplements with ____ hours of levothyroxine.
    4 hours
  3. Levothyroxine (T4)
    Synthroid, Levothroid
  4. Dessicated thyroid
    Armour Thyroid
  5. Liothyronine (T3) - 2
    Cytomel, Triostat
  6. Liotrix (T4 and T3 in a 4:1 ratio)
    Thyrolar
  7. Name the anti-thyroid meds.
    • Lugol's solution (strong iodine soln)
    • SSKI (saturated solution of potassium iodine)
    • PTU (Propylthiouracil)
    • Tapazole (Methimazole)
  8. Which drug is preferred when rapid reduction in thyroid hormone secretion is desired (like in thyroid storm)?
    Iodides - they block hormone release and inbit thyroid hormone synthesis.
  9. Cushing's syndrome is a result from chronic ________ excess.
    Glucocorticoid
  10. Which drugs are used to treat Cushing's Syndrome?
    • Ketoconazole (Nizoral) - inhibits enzymes required in cortisol synthesis
    • Aminoglutethimide ( Cytadren) - inhibts conversion of cholesterol to pregnenolone (involved in generation of glucocorticoids)
    • Mitotane (Lysodren) - cytotoxic drug that suppresses ACTH
    • Metyrapone (Metopirone) - decreases cortisol synthesis
  11. What is Addison's disease?
    Adrenocortical deficiency resulting inĀ  glucocorticoid and mineralcorticoid deficiency.
  12. What lifelong medications are needed in the treatment of Addison's disease?
    glucocorticoids and mineralcorticoids (DUH!)
  13. Cortisone

    anti- inflam: mild
    Na-retaining potency: mild
    t 1/2: short
    Cortef
  14. Hydrocortisone (3)
    Cortef, Hydrocortone, Solu-Cortef

    • anti- inflam: mild
    • Na-retaining potency: mild
    • t 1/2: short
  15. Prednisone (2)

    anti- inflam: medium
    Na-retaining potency: mild
    t 1/2: medium
    Deltasone, Liquid Pred
  16. Prednisolone (3)

    anti- inflam: medium
    Na-retaining potency: mild
    t 1/2: medium
    • Prelone
    • Pediapred
    • Delta-Cortef
  17. Methylprednisolone (2)

    anti- inflam: medium
    Na-retaining potency: none
    t 1/2: medium
    Medrol, Solu-Medrol
  18. Triamcinolone (3)

    anti- inflam: medium
    Na-retaining potency: none
    t 1/2: medium
    • Aristocort
    • Kenacort
    • Kenalog
  19. Dexamethasone (4)

    anti- inflam: High
    Na-retaining potency: none
    t 1/2: Long
    • Decadron
    • Dexameth
    • Dexone
    • Hexadrol
  20. Betamethasone

    anti- inflam: High
    Na-retaining potency: none
    t 1/2: long
    Celestone
  21. Fludrocortisone

    anti- inflam: medium/high
    Na-retaining potency: VERY HIGH
    t 1/2: medium
    Florinef
  22. What is Cosyntropin and ACTH used for?
    Diagnosis of adrenal insufficiency. Cosyntropin is a synthetic peptide that is simular to human ACTH but is less allergenic.
  23. What are all the dosage forms of testosterone?
    Patch, Gel, Injection in oil, Pellet for SQ implantation, Buccal tablet, tablets, capsules

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