Lecture 26 notecards.txt

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epaynich
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16448
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Lecture 26 notecards.txt
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2010-04-27 15:17:34
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Micro Lecture
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Micro 221 Lecture 26
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  1. Lecture 26
    ...
  2. Frank Pathogen
    Cause a disease in host
  3. Opportunistic Pathogen
    live in body normally and cause a disease when immunocompromised
  4. Subclinical Infections
    Too few or not Virulent enough to cause an infection
  5. Clinical Infections
    Cause signs and symptoms
  6. Infectious Dose
    Amount of bacteria that causes an infection; dependent on person
  7. Signs
    apparent upon examination
  8. Symptoms
    effects patient notices; ex. nausea, pain
  9. Balanced Pathogenicity
    pathogen becomes less virulent while host becomes more resistant
  10. Localized Infection
    affect the immediate area of replication
  11. Disseminated Infection
    affects area outside the area of replication
  12. Systematic Infection
    affects the whole body
  13. Bacteremia
    Bacteria that infects the blood
  14. Viremia
    Viruses that infect blood
  15. Toxemia
    Toxins that infect blood
  16. Septicemia
    acute illness caused by pathogens in blood
  17. Koch's Postulate
    used to determine the specific organism that causes a disease
  18. Infection
    Multiplication of organism causes the disease
  19. Intoxication
    Toxin produced by organism causes the disease
  20. Fimbrial adhesions
    proteins at the tip of a pili
  21. IgA Protease
    destroys IgA
  22. Siderophore
    steal iron from the host
  23. type III effector
    secrete molecules from bacterium into host cell
  24. Membrane Ruffles
    rearrangement of host cell due to type III effector that allows bacteria to hide from host
  25. Horizontal Gene Transfer
    Swapping of Genes between bacteria
  26. Pathogenicity Island
    "block" of genes for virulence factors passed between bacteria
  27. M-Cells
    specialized for transit; passes bacteria immune cells
  28. MALT
    mucousal associated lymphoid tissue containing M cells
  29. Activated Macrophage
    has enhanced oxidative burst and digestive capabilities
  30. Actin "Rockets"
    Propel bacteria from one cell to another
  31. Serum Resistance
    Block C3b activity to avoid complement pathway
  32. C3b Regulatory Protein
    Prevents C3b from activating the compliment cascade
  33. C5a Peptidase
    prevents Neutrophil recruitment
  34. Lysin
    kills phagocyte
  35. Fc Binding Protein
    Bacteria bind the wrong part of antibody so attack does not happen
  36. Staphylococcal Protein A
    ????
  37. Pilus Switching
    switching surface proteins so it isn't recognized
  38. Hyaluronic Acid
    bacteria coat in a self antigen so they aren't recognized

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