Immunosuppresants

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Author:
evelngo
ID:
164491
Filename:
Immunosuppresants
Updated:
2012-07-30 20:16:51
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Immunosuppressants
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Immunosuppressants
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  1. Cyclosporine
    Sandimmune; oral solution is Neoral

    -requires bile for emulsification and absorption
  2. Tacrolimus
    Prograf - MANY DI! known for causing HYPERkalemia. Requires therapeutic trough concentration monitoring.
  3. Sirolimus
    Rapamune
  4. Azathioprine
    Imuran
  5. Mycophenolate
    CellCept - Antacids & Cholestyramine decrease efficacy
  6. Muromonab-CD3
    Orthoclone OKT 3 - murine - must premedicate with steroids, APAP, and anti-histamine 1 hr prior to dose.
  7. Basiliximab
    Simulect -
  8. Daclizumab
    Zenapax
  9. Antithymocyte globulin (equine) - polyclonal
    Atgam - dose 1 give steroids, APAP, and antihistamines 1 hr prior to dose. Subsequent doses give APAP and antihistamines.
  10. Antithymocyte globulin (rabbit)
    Thymoglobulin
  11. List the Calcinuerin inhibitors (2)
    Cyclosporine & Tacrolimus
  12. Which one is considered an MTOR inhibitor?
    Sirolimus
  13. List the antiproliferative agents:
    • Azathioprine
    • Mycophenolate

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