Anemias

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Author:
evelngo
ID:
164564
Filename:
Anemias
Updated:
2012-07-31 12:33:53
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Anemias
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Anemias
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  1. Which types of anemia cause MACROcytic (Megaloblastic) morphology?
    • Megaloblastic anemia
    • Folic Acid deficiency
    • Vit B12 deficiency/Pernicious Anemia

    *RNA/DNA synthesis impeded, therefore cell divison is skipped resulting in abnormally large cells!
  2. Which causes normochromic, normocytic anemia?
    • Acute blood loss
    • Bone marrow failure (decreased RBCs production)
    • Hemolysis
    • Immunologic destruction
  3. What is aplastic anemia?
    Failure to produce ALL types of blood cells resulting in anemia, neutropenia, and thrombocytopenia.
  4. What anemias cause HYPOchromic (low Hgb content) or MICROcytic morphology?
    • Iron deficiency anemia
    • Sickle cell disease
    • Thalessemia

    *Lack of iron results in reduced Hgb synthesis, resulting in smaller sized RBCs.
  5. Ferrous sulfate has ___% elemental iron and is dosed at ____ mg TID.
    20% ; 325 mg

    *Iron supplementation requires 200 mg of elemental iron/day.
  6. What are the 4 available IV iron products?
    • Iron DEXtran (InFeD & Dexferrum)
    • Ferric gluconate (Ferrlecit)
    • Iron sucrose (Venofer)
    • Ferumoxytol (Feraheme)
  7. Iron needs an acidic or basic environment to be absorped?
    Acidic
  8. How much folic acid do you receive if you are deficient?
    1 mg/day x 4 months
  9. ESAs are contraindicated in patients with uncontrolled ______________.
    Hypertension
  10. Epoetin alfa
    Procrit, Epogen
  11. Darbopoetin alfa
    Aranesp

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