Card Set Information
Which types of anemia cause MACROcytic (Megaloblastic) morphology?
Folic Acid deficiency
Vit B12 deficiency/Pernicious Anemia
*RNA/DNA synthesis impeded, therefore cell divison is skipped resulting in abnormally large cells!
Which causes normochromic, normocytic anemia?
Acute blood loss
Bone marrow failure (decreased RBCs production)
What is aplastic anemia?
Failure to produce ALL types of blood cells resulting in anemia, neutropenia, and thrombocytopenia.
What anemias cause HYPOchromic (low Hgb content) or MICROcytic morphology?
Iron deficiency anemia
Sickle cell disease
*Lack of iron results in reduced Hgb synthesis, resulting in smaller sized RBCs.
Ferrous sulfate has ___% elemental iron and is dosed at ____ mg TID.
20% ; 325 mg
*Iron supplementation requires 200 mg of elemental iron/day.
What are the 4 available IV iron products?
Iron DEXtran (InFeD & Dexferrum)
Ferric gluconate (Ferrlecit)
Iron sucrose (Venofer)
Iron needs an acidic or basic environment to be absorped?
How much folic acid do you receive if you are deficient?
1 mg/day x 4 months
ESAs are contraindicated in patients with uncontrolled ______________.