Serum Enzymes and Cardiac Markers

Card Set Information

Author:
redmughead
ID:
164693
Filename:
Serum Enzymes and Cardiac Markers
Updated:
2012-08-01 11:55:00
Tags:
Lab Values
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Description:
Normal Values
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  1. Creatinine Kinase (CK)
    26-174 units/L

    Reflects tissue catabolism resulting from cell trauma

    • CK level begins to rise within 6 hrs of muscle damage
    • Peaks at 18 hrs
    • Returns to normal in 2-3 days.

    detects myocardial or skeletal muscle damage or CNS damage.

    • *CK-MB cardiac muscle: 0%-5% of total
    •   CK-BB brain tissue: 95%-100% of total
    •   CK-MM skeletal muscle: 0%
  2. LDH (Lactate Dehydrogenase)
    140-280 units/L

    • *begins to rise about 24 hrs after Myocardial Infaction
    • *peaks in 48-72 hrs
    • *returns to normal within 7-14 days

    Testing should be repeated on 3 consecutive days
  3. Troponins
    • Troponin I: <0.6 ng/mL
    •                  *>1.5 ng/mL indicates MI
    •                  * may remain elevated for 7-10 days

    • Troponin T: >0.1-0.2 ng/mL indicates MI
    •                   * may remain elevated for as long as 10-14 days

    regulatory protein found in striated muscle (skeletal and myocardial)

    *Levels elevate as early as 3 hrs after MI
  4. Myoglobin
    • <90 mcg/L
    • * elevation could indicate MI
  5. Natriuretic Peptides
    • ANP: 22-27 pg/mL
    • BNP: < 11pg/mL *primary marker for identifying CHF as the cause of dyspnea
    • CNP: not yet determined

    used to identify clients with CHF

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