Therapeutics. Exam 1.Antimicrobial medications

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Anonymous
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165017
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Therapeutics. Exam 1.Antimicrobial medications
Updated:
2012-08-04 23:31:40
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Antimicrobial medications
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Antimicrobial medications and doses
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  1. What is the dose, strength, and frequency of PCN G.
    IV 2-3 MU IV q4h
  2. What is the dose, strength and frequency of PCN VK?
    PO 250-500 mg po q6h
  3. What is the spectrum of natural penicillins (G and VK)?
    • Penicillin-susceptible streptococcus: S. pyogenes (Group A strep) and S. viridans (endocarditis)
    • PCN-susceptible: S. pneumoniae
    • Upper airway anaerobes: Peptococcus and peptostreptococcus
  4. What are the clinical uses of natural penicillins (G and VK)?
    • Upper respiratory infections: susceptibility testing necessary for S. pneumoniae
    • Bacteremias (various strep)
    • Dental infections (various strep)
    • Endocarditis (Strep. viridans)
    • Syphilis
  5. What are penicillinase-resistant PCNs used for and examples?
    • Use only for staph infections, such as methicillin-susceptible staph.
    • Nafcillin: IV 2g IV q4h
    • Oxacillin: IV
    • Cloxacillin: PO
    • Dicloxacillin: PO 250-500 mg po q6h
    • Methicillin: IV (off the market)
  6. What are the clinical uses of anti staph penicillins, such as nafcillin and dicloxacillin?
    Staph infections (MSSA and MSSE), such as cellulitis, osteomyelitis, infective endocarditis.

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