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Varicella
- Less than 20 weeks pregnancy: congenital varicella (limb hypoplasia, microcephaly, cataracts, growth retardation, skin scarring). High mortality.
- Second to third trimester: herpes zoster in an otherwise healthy infant.
- Minus seven days to plus seven days after delivery: severe and even fatal disease (30% mortality).
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Congenital CMV infection
Microcephaly, seizures, neonatal jaundice, hepatosplenomegaly, deafness and mental retardation
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Congenital CMV
Mental retardation, Spasticity, Eye abnormalities, Hearing defects, Enlarged liver
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Congenital toxoplasmosis
Risk of fetopathy is reduced by more than 50% if spiramycin, which can prevent maternal-fetal transmission, is given to mothers.
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CMV
Petechiae and hepatosplenomegaly thrombocytopenia and partially conjugated hyperbilirubinaemia. Chorioretinitis and intracranial calcification.
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CMV
jaundice, hepatosplenomegaly and microcephaly
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Toxoplasmosis
hydrocephalus, seizures and chorioretinitis.
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Rubella
cataracts, cardiac abnormalities, thrombocytopaenia and cerebral calcification.
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Rubella
- Deafness 5-7
- Cataracts 8-9
- Cardiac defects 5-10
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