Patho 3

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  1. What percent of ATP depletion leads to changes in neurologic cortical signs? (p.1)
    55% ATP depletion
  2. Neurological cortical signs
    (5)
    • speech
    • behavior
    • memory
    • judgment
    • personality
  3. At what temperature does brain cell death occur due to ATP depletion? (p.3)
    106 degrees Fahrenheit
  4. In terms of time frame, when does a seizure become a medical emergency? (p.3)
    • 20-30 minutes
    • rapid ATP depletion
  5. Review changes in blood flow during a seizure (increased or decreased). (p.2)
    • Seizure activity = rapid ATP depletion
    • Increase in CBF 250-300% to meet metabolic demands of seizure activity
  6. What is the primary energy source for brain function? (p.1)
    Glucose - converted to ATP
  7. What effect does increase in BP have on diameter of cerebral arteries? (p.6)
    • Vasoconstriction
    • Increase systemic arterial pressure or ICP
    • Prevents hyperemic flow state
  8. What effect does decreased BP have on the diameter of cerebral arteries? (p.6)
    • Vasodilation
    • Protects brain from subflow state and subsequent infarction
  9. Metabolic factors affecting brain's ability to auto-regulate. (p.7)
    • Increased PaCO2
    • Decreased PaO2
    • Brain injury
    • Intracranial bleeding
  10. Pressure changes affecting brain's ability to auto-regulate (p.7)
    • Cerebral vasodilatory drugs
    • Change in MAP
    • Increased ICP >35 mmHg longer than 20-30 minutes
    • Change in CPP
  11. MAP formula
    (p.8)
  12. CPP formula
    (p.8)
  13. Normal CPP range
    50 - 150 mmHg
  14. Average CPP
    80 - 100 mmHg
  15. CPP < 50
    Ischemia
  16. CPP > 150
    Hyperemia
  17. CPP < 30
    Incompatible with life

Card Set Information

Author:
cgordon05
ID:
16685
Filename:
Patho 3
Updated:
2010-04-29 00:23:16
Tags:
Neuro
Folders:

Description:
Neuro
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