Serotonergics

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Author:
emac0408
ID:
167993
Filename:
Serotonergics
Updated:
2012-08-29 14:10:35
Tags:
Serotonergics
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Description:
Serotonin Agonist/Antagonists
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  1. Buspirone
    • 5-HT 1A:  Anxiolytic
    • agonist
  2. Sumatriptan*
    • 5-HT 1B/1D:  mirgaines
    • agonist
    • vasoC prevents pain N stretching
    • inh release of endogenous NT (pro-inflam neuropeptide, CGRP)
  3. Cisapride
    • 5-HT 4:  GERD (withdrawn)
    • agonist
  4. Dexfenfluramine
    • anorexic (withdrawn)
    • agonist
  5. Cyproheptadine
    5-HT 2A, Musc, and H1 Blocker:  Carcinoid Syndrome, Cold-induced Urticaria, 5-HT Syndrome
  6. Ketanserin*
    • 5-HT 2A, alpha Blocker:  antiHT
    • vasoD, inh platelet agregg.
  7. Ritanserin
    • 5-HT 2A blocker:  antiHT
    • vasoD, inh platelet aggreg
    • (no block of alpha's like Ketanserin)
  8. Clozapine
    • 5-HT 7, DA Blocker:  atypical antipsychotic
    • Tx:  schizo
  9. Ondansetron*
    • 5-HT 3 blocker:  anti-emetic
    • Tx:  post-chemoTx
  10. Granisetron*
    • 5-HT 3 blocker:  anti-emetic
    • Tx:  post-chemoTx

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