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Has caused Hypothyroidism in prems
Has caused intreventricular haemorrhage in prems
Sulphonamides in pregnancy
Aspirin in pregnancy
- Premature closure of the ductus arteriosis.
- Prolonged gestation
- Neonatal haemorrhage
Aminoglycosides in pregnancy
Permanent hearing loss
Lithium in pregnancy
Foetal hydantoin syndrome=
cranio-facial abnormalities, growth impairment and learning difficulties.
Na Valproate in pregnancy
- Neural tube defect in approximately 2% of cases.
- plus abnormalities of the face and digits = the foetal valproate syndrome.
ACEi in pregnancy
Cardiovascualt compromise and transient renal failure
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