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Gastrointestinal Agents Med Chem Quiz
Gastrointestinal Agents, Med. Chem 2, Quiz 1
What are the three types of gastric ulcers?
What does GERD stand for?
Which type of an ulcer is a medical emergency?
What types of gastric or gastrouodenal contents are regurgitated during GERD?
What types of people does GERD occur in?
GERD causes injury to what?
Lumen of the esophagus
What drugs lower the esophageal sphincter tone?
What drugs are direct irritants to the esophagus?
What are some common clinical presentations of GERD?
What are some atypical presentations of GERD?
Recurrent otitis in children
Lingual dental erosion
Whata re some severe presentations of GERD?
Barrett's esophagus (adenocarcinoma risk greatly increased)
What are signs of pediatric GERD?
Cough at night
Complain of abdominal pain
Refuse to eat
Have bad taste in mouth
What are some treatment options for GERD?
Lifestyple changes (no alcohol or tobacco)
Avoiding certain foods
Eat 4-6 hours before sleeping
What acts as a buffer in the stomach?
What are the three steps in healing ulcers?
People with GI bleeds caused by ulcers may have what two presentations?
Foul odored stool containing blood
What causes GERD?
Helicobacter pylori (H. pylori)
Who discovered that GERD is caused by bacteria not stress?
J. Robin Warren
What type of bacteria is H. pylori?
Gram negative rod
How many people have H. pylori infections?
About 50% worldwid, increasing with age
Why can H. pylori survive in the stomach?
Adhere to GI cells by HpaA adhesion protein
can utilize urea and convered it to carbon dioxide and ammonia, ammonia allows bacteria to penetrate the mucous layer
What is the cold standard