Med Chem GI

Card Set Information

Author:
75ford
ID:
168949
Filename:
Med Chem GI
Updated:
2012-09-05 19:59:00
Tags:
Med Chem GI
Folders:

Description:
Med Chem GI
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user 75ford on FreezingBlue Flashcards. What would you like to do?


  1. Welchol/Colesevelam
    Bile acid sequestrant, an adjunct to diet and exercise
  2. Antimicrobials to eliminate H. pylori
    • Amoxicillin
    • Clarithromycin
    • Tinidazole
    • Rifabutin
  3. Cimetidine/Tagament
    H2 blocker, CYP 450 inhibitor, Short half-life, acidifies urine.
  4. Ranitidine/ Zantac
    • H2 blocker, NO CYP 450 inhibition
    • Must stagger dose with antacids to increase bioavail.
  5. Famotidine/Pepcid
    H2 blocker, no CYP inhibition
  6. Nizatidine/Axid
    • H2 blocker, 90% Bio, no CYP inhibition
    • May cause increase transaminase levels (liver enzyme)
  7. Omeprazole/Prilosec
    • PPI,CYP inhibitor, racemic (R is metabolized by 2C19, S by 3A4)¬†
    • Can decrease Ca+ dissolution¬†and bone resorption
  8. Esomeprazole/Nexium
    PPI, S enantiomer of omeprazole
  9. Rabeprazole/Aciphex
    PPI, CYP metabolized use caution in severe impairment
  10. Pantoprazole/Protonix
    PPI, Taken with or without food, can accumulate with hepatic dysfunction.
  11. Lansopreazole/Prevacid
    PPI, is not a CYP inhibitor
  12. Dexlansoprazole/Dexilant
    PPI, pure enatiomer of Prevacid
  13. Sucralfate/Carafate
    Makes mucus more protective, 90% is exreted in feces, little to no systemic effect. can decrease absorption of other drugs.
  14. Misoprostal/Cytotec
    Used to prevent ASA and NSAID ulcers, Increases Bicarb and mucus production, Contraindicated in pregnant women.
  15. Milk of Magnesia /Mag. Hydroxide
    Antacid
  16. Amphojel, Alu-Cap/Alumin Hydrox
    Antacid
  17. Basaljel/Alumin carb
    Antacid
  18. Calcium Carb
    antacid
  19. Mag Oxide
    antacid
  20. Riopan, Losopan/Magaldrate
    antacid
  21. Sodium Bicarb
    antacid
  22. Antacids in general
    • In renal failure dont use Alumin or Mag
    • Can get rebound hyperacidity after cronic use.
  23. Hyoscyamine sulfate/Anaspaz
    • Anticholinergic and antispasmodic (Belladonna)
    • Decreases GI secretions, spasticity
    • Take 30 min before meal
  24. Atropine Sulfate/Sal-Tropine
    • Anticholinergic and antispasmodic (Belladonna)
    • Decrease GI secretions
    • Dosing for children is weight based
  25. Scopolamine/Scopace
    • Antichol and antispas (Belladonna)
    • helps with N/V
    • adjunct in IBS therapy
  26. Methscopolamine/Pamine
    • Quatrenary anticholinergic
    • Treat peptic ulcer
    • + charge so less cross of BBB
  27. Mepenzolate/Cantil
    Quatr antichol
  28. Clininium/Quarzan
    Quatr antichol
  29. Glycopyrolate/Robinul
    Quatr antichol
  30. Dicyclomine/Bentyl
    • Treat functional/irritable bowel syndrome
    • Antispasmodic
  31. Bulk Forming Laxatives
    • Metamucil
    • Citrucel
    • Mitrolan
  32. Emmollient
    • Mineral Oil/Milkinol
    • increase the excretion of fat-soluble vit.
  33. Stool softeners
    • Docusate
    • Ex-Lax
    • Colace
  34. Hyperosmotic
    • Glycerin suppositories/Colace
    • Lactulose/Cholace
  35. Ceo-Two
    • Misc Lax
    • increases Co2 = increases Pressure
  36. Lubiprostone/Amitiza
    • Treat IBS
    • Increases Cl- WITHOUT altering K or Na, increases GI motility (acts like a saline lax)
    • Very little systemic effect
  37. Tegaserod/Zelnorm
    Treat IBS, but withdrawn from the market
  38. Budesonide/Entocort
    • Glucocorticoid for treating Crohn's
    • Relieves inflammation
  39. Infliximab/Remicade
    also (Humira)
    • TNF inhibitor
    • Treat croh'n and Rheumatoind Arth.
    • can give relief up to 12 weeks
  40. Natalizumab/Tysabri
    • Treat Crohn's and MS
    • Ultimately inhibits the inflammatory cascade
  41. Immunosupression Therapy drugs
    • Azathioprine/Imuran
    • Mercaptopurine
    • Methotrexate
    • Cyclosporine
  42. Balsalazide/Colazal
    • Aminosalicylate
    • Treat ulcerative colitis
  43. Mesalamine/Asacol
    • Aminosalicylate
    • Treat ulcerative colitis
    • tones down immune response
  44. Olsalazine/Dipentum
    • Aminosalicylate
    • Keeps ulcerative colitis in remmision
    • Is cleaved in the gut by bacteria, helps with local effect.
  45. Sulfasalazine/Azulfidine
    • Aminosalicylate
    • Treat UC and RA
    • HAs an anti-infective property
  46. Rifaximin/ Xifaxan
    • Anti-diarrheal antibiotic
    • Treat Travelers diarrhea caused by noninvasive E.Coli
  47. Motofen
    Lomotil
    • Anti-diarrheal
    • Slows GI motility
    • Has Atropine in it to keep people from abusing
  48. Loperamide/Imodium
    • Anti-diarrheal
    • Inhibits smooth muscle contraction and slows GI motility
  49. Bismuth subsalicylate/ Pepto
    • Anti-diarrheal, NV, constipation
    • Coats the linning of the gut
    • Stool will gray-black
  50. Sandostatin
    Posterior Pituitary Hormone product that helps diarrhea
  51. Somatropin/Zorbtive
    • Treat short bowel syndrome
    • Helps people absorb water
    • Watch for Pediatric gasping syndrome
  52. Simethicone/Mylicon, Gasx
    • Antiflatulent
    • A surfactant
    • Miracle drug for crying babies
  53. Charcoal
    • antiflatulent
    • High surface area to absorb
    • Can absorb wanted drugs
  54. Orlistat/Xenical
    • Lipase Inhibitor
    • Manage obesity
    • Keeps you from breaking down and using fat.
    • Prevents absorption of fat soluble vit.
  55. Metoclopramide/Reglan
    • Treat diabetic delayed GI emptying and GERD
    • Sensitizes GI to acetylcholine increaseing peristalsis
    • ***Drug induced parkinsons****
  56. Cisapride/Propulsid
    • Nocturnal heartburn
    • Can cause QT elongation (been withdrawn)
  57. Dexpanthenol/Ilopan
    • GI stimulant increase acetylcholine, increase peristalsis
    • Prophylacticly after abdominal surgery
  58. Alvimopan/Entereg
    • GI stimulant
    • Peripheral only Mu-receptor opioid antagonist
    • Doesnt take away the pain relief aspect of opioid
  59. Methylnaltrexone/Relistor
    • GI stimulant
    • Used for pt on continuous oipiod use
    • + charge doesnt cross BBB
  60. L-Glutamic acid
    Gastric acidifier
  61. Dehydrocholic acid
    Relives constipation and asan adjunct in biliary stasis
  62. Ursodiol/Actigall
    Dissolves Gall stones over a period of months
  63. Nystatin
    Oral yeast infection
  64. Tannic Acid
    canker/cold sores
  65. Clotrimazole/Mycelex
    oral yeast
  66. Chlorhexidene/ Peridex
    Gingivitis
  67. Carbamide peroxide/Gly-oxide
    Oral inflammation
  68. Pilocarpine
    Treat lack of saliva
  69. Cevimeline/Evoxac
    treat dry mouth caused by Sjogren syndrome
  70. Amlexanox/Aphthasol
    Aphthous ulcers
  71. Lanthanum carbonate
    Removal of dietary phosphate
  72. Sevelamer HCl/Renvela
    Advantage over carbonate resin is that it will maintain bicarb levels.
  73. Rectiv/Nitro
    Relax anal sphincter to treat anal fissure

What would you like to do?

Home > Flashcards > Print Preview