MED-Lidocaine

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Author:
amerelman
ID:
16931
Filename:
MED-Lidocaine
Updated:
2010-04-30 10:29:03
Tags:
MED Lidocaine
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Description:
MED-Lidocaine
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  1. Functional Class
    Class IB Antidysrhythmic (Sodium Channel Blocker)
  2. Mechanism of Action
    • Suppresses depolarization and automaticity of His-Purkinje system
    • Suppresses ventricular ectopy
    • Increases threshold for ventricular dysrhythmias
    • However, decrases ventricular threshold for fibrillation
  3. Indications
    • VF
    • Pulseless VT
    • VT with pulse
    • Malignant PVCs
    • -More than six unifocal PVCs/minute
    • -Multifocal PVCs
    • -Couplets
    • -R-on-T phenomena
  4. Contraindications
    • Hypersensitivity
    • Supraventricular dysrhythmias
    • Untreated sinus bradycardia
    • 2nd Degree Mobitz II AV block
    • 3rd Degree AV Block
    • Stokes-Adams Syndrome
  5. Precautions
    • CNS depression may occur in doses over 300 mg/hour
    • Liver or renal disease
    • CHF
    • Hypovolemia
    • Shock
    • Mysthenia gravis
  6. Side Effects
    • AMS
    • Confusion
    • Bradycardias
    • Hypotension
    • Seizures
  7. Interactions
    Use caution with Beta Blockers and Procainamide-drug toxicity may result
  8. Dosage/Route
    • ADULT CARDIAC ARREST
    • 1-1.5 mg/kg IVP repeat at half dose q 5 mins max total dose of 3 mg/kg
    • NOTE: single dose of 1.5 mg/kg acceptable if moving on to Amiodarone

    2-4 mg/kg ET q 3-5 mins

    • PEDIATRIC CARDIAC ARREST
    • 1 mg/kg IVP/IO/ET

    • ADULT WITH PULSE
    • 1-1.5 mg/kg IVP repeat at half dose q 5-10 mins max total 3 mg/kg

    • ADULT IV INFUSION
    • 1-4 mg/min
  9. Pharmacokinetics
    • Absorption: 3 mins
    • Duration: 10-20 hours
    • Half-life: 1.5-2 hours

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