pathology of the endocrine system

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Author:
Anonymous
ID:
171349
Filename:
pathology of the endocrine system
Updated:
2012-09-16 22:21:52
Tags:
endocrine
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Description:
pathology
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  1. gigantism
    • Pituitary ­
    • + Growth hormone in children
    • Tall (8 ft)Normal proportions
  2. Acromegaly
    • Pituitary 
    • + Growth hormone in adults
    • Enlarged hands,feet and jaw
  3. Dwarfism
    • Pituitary
    • - Growth hormone in children
    • Short (4 ft)Normal proportions
  4. Diabetes Insipidus
    • Pituitary 
    • - ADH
    • Polyuria and polydipsia
  5. SIADH (syndrome of inappropriate ADH secretion)
    • Pituitary
    • + ADH
    • Fluid retention (brain edema, weight gain, hyponatremia)
  6. Myxedema
    • Thyroid
    • - Thyroid hormone in adult
    • slow metabolic rate, lethargy, thick, dry skin
  7. Cretinism
    • Thyroid
    • - Thyroid hormone in infant
    • malformed, mentally retarded dwarf
  8. Grave’s Disease
    • Thyroid ­
    • + Thyroid hormone­
    • fast metabolic rate, nervousness, wt.loss, exophthalmos
  9. Cushings Disease
    • Adrenal Cortex ­
    • + glucocorticoids (cortisol)
    • hyperglycemia, muscle loss, hypertension and edema, moon face,buffalo hump, low immunity
  10. Addison’s Disease
    • Adrenal Cortex
    •  - aldosterone mineralocorticoids & glucocorticoids
    • weight loss, low Na+, high ­K+, dehydration, hypotension
  11. Pheochromocytoma
    • Adrenal Medulla ­
    • + catecholamines
    • Massive, uncontrolled sympathetic response
  12. Diabetes mellitusType I—IDDM
    • Pancreas (probably autoimmune destruction of beta cells)
    • - insulin production
    • ketoacidosis, glycosuria, polydipsia, polyuria, polyphagia
  13. Diabetes mellitusType II—NIDDM
    • Pancreas or Insulin receptors on cells
    • - insulin production or faulty receptors
    • Same as IDDM—disease on set and management different
  14. Hypoglycemia
    • Pancreas or Insulin overdose­
    • + insulin
    • hypoglycemia causing anxiety, tremors, weakness (may lead to convulsions and death)

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