A and P II

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  1. Percentages of blood composition
    • Plasma - 55%
    • Buffy coat - <1%
    • Red cells - 45%
  2. Which component is a COMPLETE cell?
    White blood cells
  3. What is the production of each type of blood cell called?
    • Erythropoiesis - red blood cell production
    • Leukopoiesis - WBC production
  4. Granulocytes and their functions
    • neutrophils - "bacteria slayers"
    • eosinophils - digest parasitic worms, modulators of the immune response
    • basophils - contain histamine (an inflammatory chemical)
  5. Agranulocytes and their functions
    • lymphocytes - acts against virus-infected cells, gives rise to plasma cells which produce antibodies
    • monocytes - crucial against viruses, intracellular bacterial parasites, and chronic infections; activates lymphocytes
  6. Which cells become plasma cells and make antibodies?
    B cells of lymphocytes
  7. The 3 phases of coagulation
    • 1. Prothrombin activator is formed
    • 2. Prothrombin is converted into thrombin
    • 3. Thrombin catalyzes the joining of fibrinogen to form a fibrin mesh
  8. What is the normal pH of blood?
    7.35 - 7.45
  9. What is the most abundant plasma protein?
    albumin (60%)
  10. Erythroblastalis fetalis
    • Rh- mother becomes sensitized when exposure to Rh+ blood causes her body to synthesize anti-Rh antibodies
    • Anti-Rh antibodies cross the placenta and destroy the RBCs of an Rh+ baby
  11. Hemophilia
    • bleeding disorder
    • hemophilia A is most common (77%) due to deficiency of factor VIII
  12. Thrombocytopenia
    deficient number of circulatiing platelets
  13. Disseminated Intravascular Coagulation (DIC)
    severe bleeding occurs because residual blood unable to clot
  14. Leukemia
    • bone marrow totally occupied with cancerous leukocytes
    • immature nonfunctional WBCs in the bloodstream
  15. Leukopenia
    abnormally low WBC - drug induced
  16. Polycythemia
    excess of RBCs that increase blood viscosity
  17. Anemia
    blood has abnormally low oxygen carrying capacity
  18. What are the causes of hypoxia?
    hemorrhage, insufficient hemoglobin, reduced availability of oxygen
  19. Rationale for rhogam treatment of Rh- women
    serum containing anti-Rh
  20. Thrombus vs embolus
    • thrombus - clot that develops and persists in an unbroken blood vessel
    • embolus - a thrombus freely floating in the blood stream
  21. plasma
    nitrogenous by-products of metabolism - lactic acid, urea, creatinine
Card Set:
A and P II
2012-09-17 23:10:06

Exam One
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