Antibiotics Examples and Spectra

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Author:
amycykho
ID:
171641
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Antibiotics Examples and Spectra
Updated:
2012-09-18 03:25:19
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antibiotics
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antibiotics
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  1. general penicillin
    • benzyl penicillin G, penicillin V
    • gram positive cocci = strept/staph
    • gram negative cocci = neiserria menin/gonor
    • gram positive bacilli = diptheria
  2. anti-staphlococcal penicillin
    • flucoxacillin
    • staph aureus (G+ cocci)
  3. anti-pseudomonal penicillin
    • ticarcillin
    • pseudomonas spp (G- bacillus - EXCEPTION)
  4. extended spectrum penicillin
    • ampicillin, amoxycillin
    • gram +/- cocci
    • gram + bacilli
    • AND E.coli, H. pylori (G- bacilli - EXCEPTION)
  5. 1G cephalosporin
    • cephazolin, cephalexin
    • G- bacilli - PEcK
    • Psuedomonas spp
    • E.coli
    • Kleibsella
  6. 2G cephalosporin
    • cefuroxime, cefoxitin, cefotetan
    • G- bacilli - HENPEck AND anaerobes
    • H. influenzae
    • Enterobactericeae
    • Neisseria (cocci)
    • e.g. community-acquired pneumonia
  7. 3G cephalosporin
    • ceftriaxone
    • same spectrum as 2G except can cross BBB
    • indicated for meningitis
    • peritonitis?
  8. 4G cephalosporin
    • cefepime
    • broad spec including both G+/-
    • reserved for severe infections
  9. non-beta-lactam cell wall inhibitor
    • vancomycin (glycopeptide)
    • MRSA
    • Clostridium difficile
  10. aminoglycoside
    • gentamicin, tobramycin
    • G- bacilli - HEPEcK
    • H. influenzae
    • Enterobactericeae
    • Pseudomonas spp
    • E.coli
    • Kleibsella
  11. tetracyclin
    • doxycycline
    • parasitic infections - G-bacilli MPC
    • malaria (Plasmodium falciparum)
    • plague (Yersinia)
    • cholera (V. cholera)
  12. macrolide
    • erythromycin, roxithromycin
    • similar to penicillin (G+) e.g. strept
    • AND atypical pneumonia - MCL
    • mycoplasma tuberculosis
    • chylamidia spp
    • legionella spp
    • AND pertussis
    • AND campylobacter
  13. chloramphenicol
    • G+/- cocci
    • anaerobes e.g. Clostridium perfringes (gas gangrene)
  14. rifampicin
    • G+ cocci e.g. staph - infection of joint prostheses
    • G- e.g. H. influenzae, Neisseria
    • M. tuberculosis
  15. fluoroquinolone
    • ciprofloxacin, moxifloxacin (RTI)
    • G- HENPEcK
    • H. influenzae
    • Enterobactericeae
    • Neisseria
    • Pseudomonas
    • E. coli
    • Kleibsella
    • CF acute exacerbations - pseudomonas
  16. metronidazole
    • anaerobes
    • e.g. Clostridium spp

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