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  1. A 16-year old girl presents with a fever, sore throat, nausea, and an enlarged spleen and liver. She tells you that there's been something going around at school and that her boyfriend has similar symptoms. Her and her boyfriend are most likely infected with which virus?

    A. Influenza
    B. Adenovirus
    C. Parvovirus B19
    D. EBV
    D. EBV
    (this multiple choice question has been scrambled)
  2. What are the 4 DNA viruses that we discussed in class that can cause respiratory tract infections? (think: P.A.C.E.)
    • Parvovirus
    • Adenovirus
    • CMV
    • EBV
  3. What are the 2 forms of Burkitt's Lymphoma?
    • Sporadic - not EBV-associated
    • Endemic form - Malaria infection is a cofactor, most common childhood cancer in Africa
  4. One of your patients, who has lived most of their life in China and recently moved to the United States, has developed nasopharyngeal carcinoma. The virus has been isolated via a tumor biopsy and a PCR has been performed. EBERs, EBNA-1, LMP-1 and LMP-2 have been expressed in the tumor cells. What virus is the likely cause of their nasopharyngeal cancer?

    A. Parvovirus
    B. Adenovirus
    C. CMV
    D. EBV
    D. EBV
    (this multiple choice question has been scrambled)
  5. Hodgkin's lymphoma, post-transplant lymphoproliferative disorders and AIDS-associated lymphomas are all associated with what virus?
  6. True or false. A hairy oral leukoplakia, an EBV infection occuring in the mouth of AIDS patients, are wart-like lesions, but are not a tumor.
  7. CMV may be shed in _____, _____, and _____ _____ _____. In diagnosing someone with CMV, you must first rule-out _____.
    urine; saliva; other bodily fluids; EBV (both infections present with enlarged liver and spleen
  8. What are the 7 clinical manifestations of adenovirus infection?
    • acute respiratory infection
    • acute respiratory disease
    • epidemic keratoconjunctivitis
    • gastrointestinal disease
    • pneumonia
    • pharynconjunctival fever
    • urethritis, cystitis
  9. What are the portals of entry and mode of transmission of the adenovirus?
    • portals of entry: respiratory tract, alimentary canal, conjunctiva/cornea
    • transmission: respiratory spread (most common), fecal oral route
  10. A vaccine for what viral respiratory tract infection has been designated for military use only?
    acute respiratory diseases (ARD)
  11. A patient who comes into your office presents with "pink eye" and a sore throat. Her eyes are red, watering, and are sensitive to light. You examine her eyes and do not find any corneal abrasions. In addition to the sore throat she has a fever, cough and nasal congestion. She tells you that her and a few friends went swimming at an indoor pool last week, and all of her friends have similar symptoms. What is the diagnosis and what is the most likely virus involved?

    A. Pharyngoconjunctival fever, influenza
    B. Epidemic keratoconjunctivitis, influenza
    C. Epidemic keratoconjunctivitis, adenovirus
    D. Pharyngoconjunctival fever, adenovirus
    D. Pharyngoconjunctival fever, adenovirus
    (this multiple choice question has been scrambled)
  12. A patient comes into your office complaining of red, watery eyes. She noticed the onset of symptoms after visiting her ophthalmologist a few days ago. You exam her eye closer and find minor corneal abrasion. What is the diagnosis and what is the most likely virus involved?

    A. Epidemic keratoconjunctivitis, adenovirus
    B. Pharyngoconjunctival fever, adenovirus
    C. Epidemic keratoconjunctivitis, influenza
    D. Pharyngoconjunctival fever, influenza
    A. Epidemic keratoconjunctivitis, adenovirus
    (this multiple choice question has been scrambled)
  13. What adenovirus types are associated with infant gastroenteritis?
    types 40 and 41
  14. _____ is the adenovirus receptor, while _____ are the adenovirus coreceptors. The virus enters the host cell via a process called _____,  where the capsid is then transported to the nuclear pore and _____ is released into the nucleus.
    CAR (coxsackie A receptor); integrins; endocytosis; DNA
  15. Match the following.

    1. adenovirus early proteins
    2. adenovirus late proteins

    A. block CTL responses
    B. block apoptosis
    C. virion structural proteins
    D. alter cell cycle
    E. replicate viral DNA
    • 1. adenovirus early proteins - A. block CTL responses, B. block apoptosis, D. alter cell cycle, E. replicate viral DNA
    • 2. adenovirus late proteins - C. virion structural proteins
  16. Which subfamily of viruses requires a helper virus (like adenovirus or herpes virus)?
  17. A 52-year old man comes into your office with complaints of flu-like symptoms, a fever, chills, malaise, myalgia and itching. He says that soon after these symptoms developed he broke out in an ugly, red rash and is now experiencing symptoms of arthritis. What is the diagnosis and what pathogen is most likely involved?

    A. Erythema infectiosum; Adenovirus
    B. Mononucleosis; CMV
    C. Mononucleosis; EBV
    D. Erythema infectiosum; Parvovirus B19
    D. Erythema infectiosum; Parvovirus B19
    (this multiple choice question has been scrambled)
  18. What congenital infection can cause a fatal condition known as hydrops fetalis?
    Parvovirus B19
  19. In the first phase Parvovirus infection symptoms, _____ response begins to clear viremia. As _____ levels begin to rise, the second phase of symptoms begin.
    IgM; IgG
Card Set:
2012-09-19 22:11:26

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