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Biochemistry Exam 1 (UF CoP)
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The 4 main components of collagen are: (Ordered by highest % to lowest)
1) Glycine GLY 2) Proline PRO
3) 4-Hydroxyproline HYP 4) 5-hyrodxylisine HYL
Two main sequences of collagen
GLY- pro -- y
GLY-x-HYP
What causes twisted helical structure in collagen
High% of proline
What does elastin lack?
Secondary structure
What is the abnormally high concentration of AA in urine?
aminoaciduria
How many AA are there in humans?
20
Which do PKU people lack?
phenylalanine hydroxylase
What is a hapten?
small molecule to which an anitbody can bind
How many AA in heavy/light chains?
440/220
What bonds hold together polpeptide chains?
Disulfide
Which Ig has the highest concentration in plasma?
IgG
Which Ig functions in mucosal secretion?
IgA
Which Ig plays a major role in allergies?
IgE
Which Ig is the 1st antibody produced in response to foreign antigen?
IgM
Which Ig can pass through the placenta?
igG
Myoglobin is a ____ with __ heme group(s)
monomer, uno
Hemoglobin is a ___ with __ heme groups
teramer, 4
What are the major anions in cell fluid?
Phosphate, bicarbonate
What is the major cation is cell fluid?
k+
What is the major cation in blood plasma?
NA+
What is the major anion in blood plasma?
CL-, HCO3-
What is an invariate residue?
An AA that does not change position (plays important role)
What is homologous?
2 sequences that are highly alignable
What is a substitution of one amino acid for another that is of similarpolarity (ex. Alanine for Valine or Apartic Acid for Glutamic Acid).
Conservative subs.
What is a substitution of one amino acid for another that is of dissimilar polarity or geometric configuration?
non-conservative
Author
Anonymous
ID
172941
Card Set
Biochemistry Exam 1 (UF CoP)
Description
Exam 1 Material
Updated
9/24/2012, 5:32:19 AM
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