Cardio studies- Lassila

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Anonymous
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173308
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Cardio studies- Lassila
Updated:
2012-09-25 13:27:02
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Cardio studies Lassila
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  1. Framingham Cohort
    population: men and women who had not developed CVD symptoms or no history of MI, heart attack or stroke

    Reason: ID common risk factors of CHD

    Primary 
  2. MR. FIT
    Population: makes with one or more risk factor

    Reason: study effects of lowering elevated serum cholesterol, diastolic pressure, and stopping smoking and if it decreased CHD mortality

    Primary
  3. HPS
    Population: men and women 40-80 that had TC >135 and an increased risk of CHD from previous Mi, disease of arteries, DM, or HTN

    Reason: examine effect of lowering LDL on CVD risks, regardless of baseline LDL

    Secondary
  4. CARDS
    Population: men and women with type II diabetes, no MI or CHD history and LDL < 160

    Reason: test if there is a decrease in major CV occurrence and if diabetics should be placed on statins

    Primary
  5. ASCOT
    Population: men and women with HTN and at least 2 risks

    Reason: decrease risk of nonfatal MI or fatac CHD event

    Primary
  6. TNT
    Population: men and women with CHD, LDL >130 TG <250

    Reason: test the difference between patients on atorvastatin 10mg and 80mg per day

    Secondary
  7. SPARKLE
    Population: ment and wonen at risk for stroke and no history of CHD LDL >100 and had previous stroke

    Reason: see if statins can decrease the risk of stroke

    • CHD primary 
    • Stroke secondary
  8. PROVE-IT
    Population: men and women with acute coronary artery disease in the past 10 days

    Reason: test pravastatin or atorvastatin in patients with MI in addition to ASA, stroke or rehospitalization 

    Secondary 

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