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To explain the behaviour of a large family in the Netherlands, where the males are affected by a syndrome of borderline mental retardation and abnormal violent behaviour.
- 5 males of the family.
- Data collection from analysis of urine over 24 hours.
- Showed a deficit of the enzyme monoamine oxidase A. MAOA.
- A mutation in the X chromosome of the gene was responsible for production of Monoanime oxidase A.
Monoamine oxidase A is involved in..
This deficit of MAOA is likely to be..
responsible for the mental retardation in the family and in turn account for the violent behaviour.
Monoamine oxidase A deficiency accounted for their inability to regulate their aggression.
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