-
Aconthosis and Spur cells
Abetalipoproteinemia
-
Basophilic Stipling
Lead Poisoning
-
Echinocytes and Burr cells
Uremia
-
Heinz Bodies
G6Pd deficiency
-
Howell-Joly bodies
- Asplenia
- Splenic Dysfunction
-
Hypersegmented Neutrophils
-
Iron inclusions in RBC of bone marrow
Ringed sideroblast cells
Polychromatophilic stipling
Nl to high Fe, ferritin and TIBC saturation
Sideroblastic anemia
-
-
Polychromasia
Reticulocytosis
-
Rouleaux formation
Multiple Myeloma
-
-
Tear dropped RBC'
Myelofibrosis
-
Microcytic anemia with nl to elevated retic count
- Hemoglobunopathy
- Thalassemia
-
Microcytic anemia with low retic count?
- Anemia of chronic disease
- Iron deficiency
- Lead poisoning
- Sideroblastic anemia
-
Normocytic anemia with nl or elevated retic count
- Acute blood loss
- Hemolytic anemia
- Medications
-
Normocytic anemia with low retic count
- Anemia of chronic disease
- Aplastic anemia
- Cancer
- Dysplasia
- Endocrine failure (TSH, Pituitary)
- Renal failure
-
Macrocytic anemia with low retic count
- B12 deficiency
- Cirrhosis, liver disease
- folate deficiency
- Methotrexate or phenytoin
-
DDx for high PT
- DIC
- Liver failure
- Warfarin Use
-
DDx for high PTT
- DIC
- Hemophilia A or B
- Heparin Use
- Severe Liver failure
- von Willebrands disease
-
DDx for high bleeding time
- DIC
- ITP
- TTP
- von Willebrands disease
-
Which coagulopathy has a high bleeding time and normal platelet count
vonWillebrand disease
-
Thrombocytopenia with hx of URI
ITP
-
Which coagulation factors use vit K?
2, 7, 9, 10
-
What is the difference between hemophilia A and B
- A: low factor VIII
- B: low factor IX
-
Difference between ITP and TTP?
TTP has low RBC
-
Treatment for TTP?
- plasmapheresis
- DO NOT GIVE PLATELETS
-
Which coag factor is not produced in the liver?
VIII
-
How do you reverse Heparin
Protamine sulfate
-
Pancytopenia, hx of radiation therapy, small child
ALL
-
Pancytopenia, auer rods DIC, over age 30
AML
-
WBC > 50,000, Philedelphia chromosome, blast crisis, splenomegaly, myelodysplasia/myelofibrosis
CML
-
Male, over 50, lymphadenopathy, lymphocytosis, infections, smudge cells, splenomegaly
CLL
-
Over 50, plaque like itchy skin rash that doesn't improve, cerebriform nuclei (butt cells) on smear, pautrier abscesses
- Mycosis fungoides
- Sezary syndrome
-
Child with hx of EBV from africa
Burkitts lymphoma
-
Cancer associated with HTLV-1
T-cell Leukemia
-
15-35 yo, Reed-Sternberg cells (owl eyes), cervical lymphadenopathy, night sweats
Hodgkins disease
-
Over 40, Bence Jones protein, Osteolytic lesions, high Ca level
Multiple Myeloma
-
Over 40, Hyperviscosity, IgM spike, Cold agglutinins
Waldenstroms disease
-
Retinoblastoma, Osteogenic sarcoma. Syndrome?
Retinoblastoma
-
Parathyroid, Pituitary, Pancreas. Syndrome?
MEN I
-
Thyroid, Pheochromocytoma, Parathyroid
MEN IIa
-
Thyroid, Pheochromocytoma, Mucosal Neuromas
MEN IIb
-
Familial polyposis, osteomas, soft tissue tumors
Gardners syndrome
-
Familian polyposis, CNS tumors
Turcots syndrome
-
Perioral freckles, non-cancerous GI polyps, non-colon cancer.
Peutz-Jeghers
-
Neurofibromas, cafe-au-lait spots, pheochromocytomas, bone cysts, Wilms tumor, leukemia
Neurofibromatosis type 1
-
Bilateral acoustic schwannomas
Neurofibromatosis type 2
-
Hemangiomas in cerebellum, renal cell cancer, cysts in liver/kidney.
von Hippel-Lindau disease
-
Stomach cancer that spreads to ovaries
Krukenberg tumor
-
10-30 yo, sunburst or codmans triangle in distal femur or proximal tibia
Osteosarcoma
-
Liver tumor in child
Hepatoblastoma
-
Woman of reproductive age taking OCP with tumor in liver
Hepatic Adenoma
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