HIV

Card Set Information

Author:
kchardy
ID:
175629
Filename:
HIV
Updated:
2012-10-04 20:43:22
Tags:
AIDS HIV
Folders:

Description:
Cellular destruction
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  1. What are the primary cells HIV targets
    • CD4-helper T cells
    • Dendritic cells¬†
    • Macrophages
    • Natural Killer cells
  2. How does HIV induce aptoptosis
    HIV infected cells shed soluble ciral envelope gp120, which can induce apotptosis of uninfected T lymphocytes, neurons, monocytes through interaction on the cell surface receptors.
  3. What are the receptor cells on the HIV and cell surface that interact
    CD4 cell of the Helper T and gp120 on the HIV virus. 
  4. Once CD4 and gp 120 have fused, what happens
    HIV virus is injected into the cytoplasm
  5. What is special about the retrovirus HIV
    It is converted into a double stranded DNA provirus by action of the viral reverse transcriptase
  6. What happens to the immune system when infected with HIV
    HIV attacks the immune system cells and destroys ability to fight infection. (lymphocytes, phagocytes, macrophages)
  7. What body systems are affected by the HIV virus
    • Lymph nodes
    • Brain
    • Thymus
    • Bone Marrow
    • Lung
    • Skin
    • Colon
  8. At what point in the HIV process do the drug interactions work
    Reverse transcriptase and Viral protease

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