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Neuromodulator
A chemical messenger that communicates with target cells more distant than the synapse by diffusing away form the point of release
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Neurohormone
A chemical messenger that communicates with target cells at great distance, often by traveling through the circulation
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Neurotransmitter
A chemical messenger that communicates across a synapse
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Muscarinic receptor
A postsynaptic receptor that responds to both ACh and muscarine
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Nicotine receptor
A postsynaptic receptor that responds to nicotine and ACh
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(AChE) acetylcholinesterase
An enzyme that breaks down the neurotransmitter acetylcholine
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(ACh) acetylcholine
A major small-molecule neurotransmitter used at the neuromusclar junction, in the autonomic nervous system, and in the central nervous system
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Indolamine
One of a subgroup of monoamines, including serotonin and melatonin
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Monoamine
One of a major group of biogenic amine neurotransmitters, including dopamine, morepinephrine, epinephrine, and serotonin
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Catecholamine
A member of a group related biogenic amines that includes dopamine, epinephrine, and norepinephrine
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Epinephrine
One of the monoamine/ catecholamine neurotransmitters; also known as adrenaline
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(MAO) Monoamine oxidase
An enzyme that breaks down monoamines
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Norepinephrine
A major monoamine and catecholamine neurotransmitter
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Dopamine
A major monoamine and catecholamine neurotransmitter implicated in motor control, reward, and psychosis
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(NO) Nitric oxide
A gas that performs a type of signaling between neurons
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Serotonin
A major monoamine and indolamine neurotransmitter believed to participate in the regulation of mood, sleep, and appetite
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(GABA) gamma-aminobutyric acid
A major inhibitory amino acid neurotransmitter
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Adenosine
A byproduct of adensoine triphosphate (ATP) that functions as a neurotransmitter
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Glutamate
A major excitatory amino acid neurotransmitter
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Placebo Effect
Perceived benefit from inactive substances or procedures
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Area Postrema
A brainstem area, in which the blood-brain barrier is more permeable, that triggers vomiting and response to the detection of circlating toxins
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Nucleus Accumbens
A dopaminergic structure believed to participate in reward and addiction
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Addiction
A compulsive craving for drug effects or other experiences
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Withdrawl
The symptoms that occur when certain addictive drugs are no longer administered or are administered in smaller quanities
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Tolerance
The process in which more of a drug is needed to produce the same effect
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Agonist
Substance that promotes the activity of a neurotransmitter
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Antagonist
Substance that reduces the action of a neurotransmitter
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Nicotine
A stimulant drug that is the major active component in tabacco
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(GHB) gamma hydroxybutyrate
An illegal liquid sedative that appears to affect the thresholds of respones for a number of neurotransmitters
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(THC) tetrahydrocannabinol
The major ingredient of cannabis
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(LSD) lysergic acid diethylaminde
A hallucinogenic drug that resembles serotonin
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St. John's Wort
An herb that is frequently used to selftreat mild depression
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(PCP) phencyclidine
A hallucinogen that acts as an antagonist at the NMDA glutamate receptor
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Mescaline
The active hallucinogenic ingredient found in the peyote cactus
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Caffeine
A stimulant drug found in coffee, tea, cola, and chocolate that acts as an antagonist to adenosine
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Psychoactive drug
A drug that produces changes in mental processes
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(MDMA) Ecstasy
A close relative of amphetamine that produces it behavioral effects by stimulating the release of serotonin
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Endorphin
A naturally occuring neuropeptide that is very closely related ot opioids
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Amphetamine
A highly addictive drug that acts as a potent dopamine agonist
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Opiate
An active substance derived from the opium poppy
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Methamphetamine
A variation of amphetamine that is cheaply produced and widely abused in the United States
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Cocaine
A powerful, addictive dopamine agonist derived from the leaves of the coca plant of South America
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