Card Set Information
Child presents with bowing of the tibia, flattened nose, and deafness. Tx of mother to avoid this?
: Pen G
Patients with septic athritis get recurrent infections with Neisseria due to?
Antigenic and phase variation of the pili
OMP I - structural, used in serotyping
Opa proteins - antigenic variation, adherence
IgA protease - colonization + cellular uptake
Medullary thyroid carcinoma
Parafollicular cells of the thyroid - NC cells
Calcitonin precipitates to form amyloid
High fever for a long time
Palpable cervical lymph nodes
Desquamating rash on palms, soles and mouth
Can damage coronary vessels causing aneurysms
Reflex that disappears between 3-6 months
: extension and abduction of arms followed by flexion and adduction
Caused due to a startling event
Reflex that disappears in 1 month
Palmar grasp reflex: Infants hand closing over an object placed in their hand
Paget's disease - viral pathogenesis?
Paramyxoviruses in the osteoclasts
Alcoholic presents with hemorrhages around hair follicles, echymoses. Vitamin deficient?
Microvilli - what proteins affected?
Actin (microvilli are extensions of actin filaments)
Myosin (binds to actin)
One hour after exercise - what increases?
VEGF mRNA = growth of new blood vessels decreases diffusion distance between capillaries and muscles, and improves oxygen transport
Decreases myoglobin O2 saturation and intracellular O2
Few days later: increases mitochondrial volume density
Body reaction to parasites
Coats them with IgE molecules
Triggers eosinophilic-mediated cytotoxicity
Release of vasoactive and spasmotogenic peptides from mast cells and basophils
12 hours after exercise, mechanism working to produce glucose?
(first few hours = hepatic glycogenolysis)
Clomipramine (TCA drug)
Test to detect viral load in HIV
Test to detect pneumonia caused by AIDs
Test to measure progression of infection by HIV
Direct fluorescent antibody test/Methamine silver stain (P. jiroveci)
CD4 T cell count
Celecoxib over general NSAIDs
Doesn't inhibit COX-1
: less GI irritation and renal impairment
: Sulfa allergy
Severe anemia can cause heart failure. Values in the blood?
Hypoxia in the tissues
Small arterioles and arteries dilate
Heart continues to pump with a greater force to allow more blood and oxygen to go to the tissues
Enveloped, DNA virus
Causes molluscum contagiosum
DNA-dependent RNA polymerase
Replicates in the cytoplasm
Cryptococcus meningitis - test?
Latex agglutination test to detect capsules shed in the CSF
(India Ink is not specific)
Ashkenasi Jews associated with which diseases
What stage of germ cell located near the basal lamina in the seminiferous tubule?
Spermatogonia (2N cells)
Baroreceptor reflex due to a decreased blood pressure
Increased SNS leading to increased NE release - increases a1 receptors = Gq receptors increases DAG and IP3
What allows emboli forming in the veins to bypass lungs and cause emboli in the arteries in the systemic circulation (e.g. brain)
(PE will produce emboli in the lungs but will not be able to bypass to go to the systemic circulation)