UMMC Micro test2 5th

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sullydog101
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176206
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UMMC Micro test2 5th
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2012-10-08 09:06:18
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UMMC Micro test2 5th
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UMMC Micro test2 5th
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  1. What is the result of the Tn 1546 mediated vancomycin resistance pathway?
    • VanX breaks down D-Ala-D-Ala to D-Ala
    • VanH turns pyruvate into D-Lac
    • VanA adds D-Lac to D-Ala
    • End result is D-Ala-D-Lac instead of D-Ala-D-Ala
  2. What causes generalized transduction with regard to viruses?
    Packing error packs first infected cells DNA into virus instead of virus DNA in a lytic life cycle bacteria
  3. What causes specialized transduction?
    Excision errors from a lysogenic life cycle bacteria
  4. What is a defective prophage?
    A phage that can no longer form infective phage particles although parts are retained due to useful trait
  5. Which element from Acinetobacter baumannii encodes 45 antimicrobial resistance genes and 2 gene capture integrins?
    AbaR1
  6. What element from Staph aureus converts antibiotic susceptible S. aureus in MRSA?
    SCCmec
  7. Fosfomycin inhibits one of the enzymes that converts UDP-NAG to UDP-NAM. Assuming that all UDP-NAM is unavailable, what steps in peptidoglycan synthesis would then be prevented?
    – A. Polymerization of stem peptides
    – B. Loading of bactoprenol phosphate carrier
    – C. Transglycosylation reactions to assemble glycan strands
    – D. Transpeptidation reactions to crosslink stem peptides
    – E. All of the above
    E. All of the above
  8. A bacterium that is susceptible to infection with virulent (lytic) bacteriophage, and is devoid of transposons, plasmids, and prophage, might still be able to transfer antibiotic resistance genes to other bacteria by which mechanism:
    A. Simple transposition
    B. Generalized transduction
    C. Replicative transposition
    D. Conjugation
    E. Specialized transduction (no b/c no prophage
    B. Generalized transduction
    (this multiple choice question has been scrambled)
  9. A plasmid is:
    A. An autonomous replicon
    B. Without medical relevance
    C. Always a supercoiled DNA molecule
    D. Always indispensable for cell division
    E. A molecule that is always integrated in the chromosome
    A. An autonomous replicon
    (this multiple choice question has been scrambled)
  10. Transformation:
    A. Can be defined as horizontal genetic transfer via a virus without tail fibers
    B. Is a type of intracellular DNA transfer
    C. Can be defined as horizontal genetic transfer via cell-cell contact
    D. Can be defined as horizontal genetic transfer via uptake of naked DNA from the environment
    E. None of the above
    D. Can be defined as horizontal genetic transfer via uptake of naked DNA from the environment
    (this multiple choice question has been scrambled)
  11. Genetic variation in bacteria can be caused by all of the following EXCEPT:
    A. Deamination of a methylated cytosine
    B. Transposition
    C. Lysogenic conversion
    D. Simple point mutation
    E. Latency
    E. Latency
    (this multiple choice question has been scrambled)

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