Physio-1

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Author:
atmu
ID:
176443
Filename:
Physio-1
Updated:
2012-10-09 01:05:00
Tags:
Physio
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Description:
Physio-1
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  1. Classification of Infarcts (2):
    1.Transmural:  more common / involve the entire thickness of myocardium

    2. Subendocardial:  less common / only involve inner portions of myocardium
  2. Early Cellular Changes of Infarct (2):
    • 1.Altered ion gradients
    • 2. Drop in intracellular pH
  3. Early Tissue Changes of Infarcts(4):
    • 1.­ vascular permeability
    • 2.Tissue edema (wavy fibers)
    • 3.Neutrophil infiltration
    • 4.Coagulation necrosis
  4. Late Tissue Changes of Infarcts (2):
    • 1.Resorption of dead tissue
    • 2.Fibroblasts deposit new collagen matrix (fibrosis) 
  5. What are the Consequences of Transient Ischemia at the Tissue Level (5)?
    • 1.Myocytes revert to glycolysis
    • 2.LessATP is being produced
    • 3.Morelactic acid being produced
    • 4.Decrease in systolic contraction and diastolic relaxation
    • 5.Accumulationof waste products stimulates pain receptors
  6. What are the Consequences of Transient Ischemia at the Organ  System Level (4)?
    • 1.Pain triggers discharge of both sympathetic and parasympathetic systems
    • 2.Increased sympathetics trigger increased heart and respiratory rates
    • 3.Increased parasympathetics trigger nausea
    • 4. Decreased systolic contraction and diastolic relaxation lead to pulmonary congestion

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