Med Chem quiz 5

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75ford
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176639
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Med Chem quiz 5
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2012-10-09 20:05:38
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Med Chem quiz
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Med Chem quiz 5
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  1. Sotalol/Betapace
    • Ethanolamine B-blocker
    • 0% protein bound
  2. Propranolol/Inderal
    • Non-selective B-blocker
    • Lipid soluble
    • Treat pheochromocytoma, at low dose stage fright.
    • PTSD and Infantile Hemangiomas
  3. Timolol/Blocarden
    • Non-selective B-blocker
    • Treat MI Migraine prophylaxis
  4. Penbutolol Sulfate/Levatol
    • non-selective B-blocker
    • Used when a B-blocker is needed but you dont want to slow down the heart.
  5. Nadolol/Corgard
    • non-selective B-blocker
    • dosage needs reduced in renal failure
  6. Pindolol/Visken
    • non-selective B-blocker
    • Provides less resting bradycardia
  7. Carteolol/cartol
    • non-selective B-blocker
    • Has less resting brady effects
  8. Atenolol/Tenormin
    • B1-blockern
    • At high dose you lose selectivity
  9. Metoprolol/Lopressor
    • B1-blocker
    • Used to prevent cardiac remodeling
    • Avoid the extended release form for presergical treatment
  10. Bisprolol/ Zebeta
    • B1-blocker
    • Treat hypertension
    • 50% renally excreted unchanged
  11. Betaxolol/Kerlane
    • B1-blocker
    • 80% excreted in urine
    • Starting dosage for elderly is 5mg
  12. Esmolol/Brevibloc
    • B1-blocker
    • Treat Supraventricular tachy
    • Extreme metabolism by esterases in RBC
    • Incompatable with sodium bicarb
  13. Acebutolol/Sectral
    • B1-blocker
    • Has less resting brady
    • Treat ventricular arrhythmias
  14. Nebivolol/Bystolic
    New B1 that also modulates nitric oxide system (increase)
  15. Labetalol
    • Non-selective B and A blocker
    • Treat Clonidine withdrawl
    • Not compatable in basic solutions
  16. Carvedilol
    • A and B blocker
    • Prodrug
    • Treat essential hyper
    • Metabolite is 14x stronger b blocker
    • First to show pharmacogenomic factors
  17. Prazosin/Minipress
    • selective A1
    • Treat BPH and Hyper
  18. Trazosin
    • A1 selective
    • Treat BPH
    • First dose causes postural hypotension
  19. Alfuzosin
    • Non-steroidal for BPH
    • Selective blocker of SM A1 receptors
    • Possible QT
  20. Silodosin/Rapaflo
    • Non-steroidal for BPH
    • More selective
    • No QT
  21. Doxazosin
    • Selective A1
    • First dose hypo
  22. Tamsulosin
    • A1 selective (38 fold)
    • One of themost popular
    • Sulfa Allergy
  23. Methyldopate and Methyldopa
    Centrally acting anti-adrenergic
  24. Clonidine/Catapres
    • Centrally acting anti-adrenergic
    • Treat ulcerative colitis
    • Severe rebound hyper possible
  25. Guanabenz/Wytensin
    • Centrally acting anti-adrenergic
    • Rarely used
  26. Guanfacine
    • Centrally acting anti-adrenergic
    • Rarely used
  27. Reserpine
    • Agent that depletes neurotransmitter stores
    • Depletes catacholamines
  28. Guanadrel/Hylorel
    • Depletes catacholamines
    • Treat hyper not responding to thiazides
  29. Mecamylamine
    • Depletes catachol
    • Not common
    • Dose determined by trial and error
  30. Guanethidine
    • Depletes catachol
    • Inhibits the release of norepi
  31. Cleviprex
    • Ca blocker
    • Contra in soy/egg allergy
    • Injectable Emulsion
  32. Sodium Diazoxide/HyperStat
    • Potassium Channel Blocker for emergency hyper
    • Also treats Hyper insulinism
    • Not effective against Pheochromo
  33. Fenoldopam
    • Dopamine agonist for hyper emergency
    • Used short term

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