Patho 3

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  1. HPT, HPA, HPG
    (insert between p.9 & 10)
    • endocrine system
    • hormones released from hypothalamus
    • affects release of pituitary hormones and target endocrine glands (adrenals, thyroid, gonads)
  2. What hormonal changes are indicative of menopause?
    • decreased estrogen from ovaries
    • stimulates increased FSH from pituitary gland
  3. T3
    metabolic regulator between 2 extremes -- hyperthyroidism and hypothyroidism
  4. What physiologic effect will T3 have on beta-adrenergic receptors and, in turn, on clinical s/s of hypothyroidism or hyperthyroidism?(p.7)
    increase synthesis of beta-adrenergic receptors --> increase formation of hormone-receptor complexes --> increase biologic activity
  5. S/S of Hyperthyroidism
    • increased beta-adrenergic activity
    • = tachycardia
    • = increased cardiac output
    • = wide pulse pressure
    • = decreased peripheral vascular resistance
    • = anxiety
    • = eyelid retraction - starring expression due to contraction of Muller's muscle
    • = warm skin (heat dissipation)
    • = sweating
  6. How can clinical s/s of hyperthyroidism be eliminated?
    Beta-adrenergic blockers
  7. Hypothyroidism
    • impaired beta-adrenergic synthesis
    • may allow alpha-adrenergic receptor activity to predominate
    • = increased peripheral vascular resistance = increased BP (esp. with Hx of Htn)
  8. What pituitary hormone is released in response to hypovolemia and increased serum osmolality?
    Antidiuretic hormone (ADH)
Card Set
Patho 3
endocrine thyroid pituitary
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