Pharm: Antihypertensives

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Author:
BrookeNH10
ID:
179006
Filename:
Pharm: Antihypertensives
Updated:
2012-10-22 13:04:31
Tags:
Antihypertensive Drugs
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Description:
Antihypertensive Drugs
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  1. Categories of Hypertension
    • <120, <80 = Normal
    • 120-139, 80-89 = Prehypertensive
    • 140-159, 90-99 = Stage 1 HTN
    • >160, >100 = Stage 2 HTN
  2. Hypertension in Diabetes?
    >130, >80
  3. Contemporary Antihypertensive Drug Classes & Targets
    • Diuretics (Kidney):  Thiazides, Aldosterone Antagonists
    • Sympathetic Nervous System Inhibitors:  Adrenoreceptor Blockers (B-Blockers, a1-blockers, a1/B-Blockers), Centrally Active Agents, Adrenergic Neuron Blockers
    • Renin-Angiotensin Inhibitors:  ACE Inhibitors (ACEIs), Angiotensin Receptor (AT1) Blockers (ARBs), Renin Inhibitor
    • Ca2+ Channel Blockers
    • Direct Arterial Vasodilators
    • Hypertensive Crisis:  Nitroprusside, Diazoxide, Fenoldopam
  4. Drugs Used for Less Selectivity: Often Monotherapy
    • Diuretics
    • B-Adrenoreceptor Antagonists
    • ACE Inhibitors/ AR Blockers
    • Ca2+ Channel Blockers
  5. Diuretics
    • Thiazide:  Hydrochlorothiazide (chlorthalidone, metolazone, indapamide)
    • Adosterone Antagonists/ Potassium Sparing:  Spironolactone, Eplerenone
    • Loop Diuretics
    • Furosemide

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