Causes skin sensitivity & can make a "blue mask" with overexposure to the sun.
Class III - K Channel Blocker -> Multaq
Used for AF/Flutter with RVR
Benefit: not as many SE as does Amiodarone
Class III - K Channel Blocker -> Multaq SE?
FDA warning R/T dronaderone causing elevation of LFT & bilirubin especially during the first 6 months of therapy.
Black Box Warning: Pt's with decompensated HF and are on a dronaderone had a greater than twofold increase in mortality. The use of dronaderone is contraindicated in pt's with NYHC IV or recently decompensated NYHC II or III.
Class III - K Channel Blocker -> Amiodarone, Tikosyn, Multaq Action?
Commonly given to convert a pt. from A-fib/flutter with RVR back to SR.
May also be given to patients who require cardioversion to SR or have recently cardioverted, to maintain SR.
Part anti-dysrhythmic & part beta-blocker & is not a first line drug; used when other antiarrhythmic medications have failed.
Improve cardiac contractility which results in decreased end diastolic volume and increased Cardiac Output:
Used in A-fib, A-flutter
N/V, abdominal pain & bloating
H/A, fatigue, malaise
Flashes of yellow lights, hazy vision, flickering images
Potassium levels (hypokalemia) & digitalis
Apical pulse (one min.)
Many Drug-Drug interaction: don't give with Amiodarone
Therapeutic Level: 0.5-2
Given IV (reverses in 30 min).
Reserved for life-threatening overdose in pt's who are in shock or cardiac arrest or have severe ventricular dysrhythmias with a potassium >5 mEq/L.
Can cause hypersensitivity reactions.
Note: Digoxin CANNOT be restarted until Digibind is eliminated from the body (takes several days in pt's who have normal renal function).
Magnesium Sulfate (not an antiarythmic)
Electrolyte used to treat refractory VT or VF
Hypomagnesemia causes ventricular irritability
Used to treat Torsades that often results from other antidysrhythmics