Home > Preview
The flashcards below were created by user
on FreezingBlue Flashcards.
Where is hyaline cartilage found in the body? Function?
- 1) Fetal skeletal tissue
- 2) synovial joints
- 3) Trachea
- 4) others
- 1) resists compression (cusioning)
- 2) lowers friction
- 3) structural support (e.g. trachea)
- 4) endochondral ossification
Where is elastic cartilage found in the body? Function?
- 1) pinna of ears
- 2) larynx
- 3) auditory tube
- 1) Provides flexible support
Where is fibrocartilage found in the body? Function?
- 1) intervertebral discs
- 2) menisci
- 3) some joints
- 4) insertion of tendons
- 1) resists deformation under stress
What are some characteristic features of each cartilage type?
- Type I collagen (produced by fibroblasts)
Describe the development and growth of cartilage
- Develops from the condensation of mesenchyme mesenchymal SC differentiate into chondroblasts
- appositional growth:
- (at the edge) under perichodrium
- Interstitial growth:
- Chondroblasts/chondrocytes divide and then secrete matrix (isogenous groups)
Describe the steps in collagen formation.
- 1) transcription of mRNA
- 2) Translation into polypeptides
- 3) Hydroxylation of lysines and prolines. Uses vitamin C as a cofactor. this aids in the crosslinking of alpha peptides (making the helix)
- 4) golgi apparatus modification
- 5) formation of tropocollagen
- 6) formation of collagen fibril
Describe the structure of the perichondrium and its function in cartilage growth/repair.
- Fibrous CT
- - Provides vascular and nervous supply
- - perichondrial fibroblast-like cells differentiate into collagen II - producing cells
describe the growth, regeneration, and structure of articular cartilage.
- no perichondrium, therefore there is very limited ability for self repair as mature chondrocytes dont readily divide
- remember your zonation from M.Sc.
- damaged cartilage is replaced by fibrovascular cartilage
What is the difference between innervation and blood supply in bone and cartilage?
- bone is highly vascular while cartilage is avascular
- cartilage is not innervated while bone is
How does cartilage recieve nutrition and exchange metabolites?
What causes cartilage to mineralize?
- 1) advanced age
- 2) trauma
- 3) naturally during growth and development
What would you like to do?
Home > Flashcards > Print Preview