Pharmacology Final

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Author:
Anonymous
ID:
18071
Filename:
Pharmacology Final
Updated:
2010-05-06 01:38:36
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Drugs Know
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Drugs to Know
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  1. Insulin Lispro
    • Ultra Short Acting Insulin
    • 15-30 min onset
    • 1-2 hour max
    • 4-6 hour duration
  2. Regular Insulin
    • Short Acting Insulin
    • 30-60 min onset
    • 2-3 hour max
    • 6-8 hour duration
  3. NPH Insulin
    • Intermediate Acting Insulin
    • 2-4 hour onset
    • 4-6 hour max
    • 14-18 hour duration
  4. Insulin Glargin
    • Long Acting Insulin
    • delayed onset with a long-term effect (24 hours)
  5. Pramlintide
    • A synthetic Amylin
    • -decreases gastric mobility
    • -decreases appetite
    • -lowers glucagon secretion
  6. Metformin
    • Increases the hepatic response to insulin
    • the first choice drug to increase insulin response
    • cannot produce hypoglycemia
  7. Rosiglitazone/Pioglitazone
    • Promotes insulin induced glucose uptake
    • often used with meformin
    • produces edema (not safe for bad heart)
    • doesn't produce hypoglycemia
  8. Glimepiride
    • increases insulin secretion (used for type 2 w/ decreased insulin production)
    • a sulfonylurea (sufa drug)--> sulfa allergy
    • chronic use will develop a tolerance
    • may produce hypoglycemia (via insulin)
  9. Repaglinide
    • increases insulin secretion (used for type 2 w/ decreased insulin production)
    • shorter duration and faster onset then Glimepiride
    • taken before meals
    • used primarily when Glimepiride is not effective
    • may produce hypoglycemia (via insulin)
  10. Exanatide
    • increases insulin secretion and liver response (a drop in glycogenolysis and gluconeogenesis)
    • an incretin mimetic
    • must be injected
    • may produce hypoglycemia (via insulin)
  11. Sitagliptin
    • increases insulin secretion and liver response (a drop in glycogenolysis and gluconeogenesis)
    • increases incretin levels by preventing breakdown (inhibits DPP-4)
    • may be taken orally
    • may produce hypoglycemia (via insulin)
  12. Acarbose
    • prevents oligosaccharide breakdown in GI by inhibiting intestinal enzyme
    • less carbohydrates entering body --> lower systemic glucose
    • produces gas

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