Path Test 2: WBCs
Home > Preview
The flashcards below were created by user
on FreezingBlue Flashcards.
Infection of B-ells with EBV through the CD21 protein
AD or AR?
- Bilobed, unsegmented neutrophi nuclei
- Normal neutrophil function
Acquired Pelger-Huet anomaly is seen in
Myelodysplasia or myeloid leukemia
Light blue cytoplasmic inclusions
RNA remnants or rER
Observed in infections and inflammatory states
Neutrophil nuclear hypersegmentation:
> 5 lobes
- Inherited Deficiency
Granulocyte transfusion (severely neutropenic pats with fever or infection unresponsive to antibiotics or antifungal agents)
Myeloproliferative Neoplasms (Chronic Myeloproliferative Disorders)
- CML (Chronic Myelogenous Leukemia)
- PV (Polycythemia Vera)
- ET (Essential Thrombocythemia)
- Primary Myelofibrosis
3 Stages of CML
- Chronic Phase
- Accelerated Phase
- Blast Phase
Philadelphia chromsome found in?
How do you differentiate CML from Leukemoid rxn?
Which one has more leukocyte alkaline.
- CML has basophilia, eosinophilia, and nucleated RBCs.
- Leukemoid rxn has mainly banded PMNs while CML has the whole spectrum.
- Leukmoid has more Leukocyte alkaline
Drug directed against abnormal tyrosine kinase in CML.
Polycythemia Vera is ____
3 increased cell types
Faster or slower blood flow?
- Increased RBC (>Hct 60%); slower blood flow
- Erythroid, Granulocytic, and megakaryocytic cells are all increased
Essential Thrombocytopenia (ET) is a hematopoietic stem cell disorder that primarily affects
Megakaryocytic cells (Platelets are increased, Giant platelets in the blood)
Plateles more than 450k
Hypercellualr marrow with large dysplastic and clustering megakaryocytes
What would you like to do?
Home > Flashcards > Print Preview