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Migraineur
A person who suffers from migraine attacks
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Characteristics of Migraine
- chronic pain for hours or days
- more common in women than men
- usually begins late teens to early twenties
- duration ranging from 4 to 72 hours and frequency recurrent or widely variable
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2 types of Migraine
- Presence of an aura - classic
- Absence of an aura - common
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Symptoms of Migraine
- moderate to severe throbbing one (60%) or 40% sides
- preceeded or accompained by sensory warning symptoms or signs (auras or premonitions)
- increased sensitvity ot sight, sound, and/or smell
- visual blurring
- nausea/vomiting
- numbness
- dizziness
- increased pain with routine physical activities
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Causes of Migraine
- vascular theory - inappropraite constriction/dilation of arteries in occipital lobe
- Serotonin (5-HT) theory - low 5-HT levels in the brain may trigger a migraine by causing arerial vasospasms (triptians 5-HT receptors agonists) alleviate migraines by activating seroton recptors
- Neural theory - brianstem nerves become irritated releaseing inflammatory neuropetides increasing pain receptors
- Unifying theory - (vascular and nueral influences) 5-HT cause arteral vasospasm, while neuropeptides casue neurogenic inflammation and pain
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What are risk factors of Migraine
- Family history
- heredity
- environmental
- age
- gender
- hormones
- patent foramen ovale in heart
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Medicaiton for Migraine
- 2 types
- 1-Pain-relieving - acute or aborative drugs taken to disrupt migrain attach
- NSAIDS
- Combo meds (NSAIDS with caffeine)
- Triptans
- ergots alkaloids
- anit=nausea meds
- barbituates
- opiates
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Preventive medication for Migraine
- Drugs taken daily to reduce the serverity or ferq of a Migraine attack
- 50% of migraineurs may benifit although only use in 10%
- 1- 2 or more debilitating attacks a month
- 2- pain-releveing medications ineffective
- 3-signs symptoms such as prolonged auras or numbness and weakness
- Cyproheptadine Antidepressants
- Methysergide Anti-seizure medications
- Antihypertensive medications Botulinum toxin type A
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