SA Med, Q2, VII
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What is the most common cause of lower urinary tract signs in cats?
What is the significance of crystalluria in cats with no clinical signs?
What is hemorrhagic inflammation of the bladder/urethra of unknown cause in felines?
feline idiopathic cystitis
Lower urinary tract infections are very rare in cats of what age?
very rare if <10years old (possible if older than 10)
What human condition is related to FIC because both share irritative voiding, increased frequency+/- hematuria of unknown cause?
Is FIC an acute or chronic disorder? are signs persistent or intermittent?
- chronic disease
- persistent waxing and waning signs, frequently recurs
Are males or females more likely to get FIC?
- equal occurrence with neutered/spayed at increased risk
- (NOT associated with narrow urethra in males as is often thought)
with regard to clinical signs for to idiopathic cystitis, what does FISHY stand for?
- F= increased Frequency
- I = inappropriate urination; Irritative voiding
- S = stranguria
- H = hematuria
- Y = yowling
what is the #1 cause of lower urinary tract disease in cats <10 years old? What is the prevalence of UTI as the cause?
- idopathic (63%)
- UTI only 1%
What is #1 cause of lower urinary tract disease in cats greater than 10 years?
- UTI (46%)
- UTI + stones (17%)
Do dogs have a similar syndrome to FIC?
no, most dogs have identifiable reason for their lower urinary signs (bacterial UTI, stones, etc)
How common is FIC in the overall cat population?
<1% (not a common disease in cats but a fairly common reason to present to clinic)
of all proposed etiology for FIC, which is the most regularly associated finding?
highly concentrated urine (high SG)
Diet, Stress, Genetics, and age of neutering are all proposed etiology for FIC. Which is actually incorrect bc it is NOT associated with FIC?
age of neutering is not a factor
Is dry or wet food the culprit of FIC?
- dry food
- (incr. drinking and fecal water --> decr. urine volume/incr SG)
How long does an episode of FIC usually last?
get better in 5-10 days regardless of treatment
What are some of the pathophysiology factors?
- upregulated sympathetic outflow***
- abnormal bladder permeability
- altered GAG layer
- mast cell infiltration
Are NSAIDS or anti-inflammatory doses of steroids helpful for FIC patients?
no, they don't help
what is the neurogenic inflammation theory?
sympathetic nervous system overactivity is damaging bladder innervation -OR- inflammed bladder leads to over stimulation of symp.system
What does abnormal bladder permeability result in?
"leaky" bladder with urine permeating through bladder wall
What are the 3 main factors involved in the pathophysiology of FIC?
- "sensitive" cat in a "provocative" environment
Persians or Siamese cats are more often associated with FIC?
persians more (siamese less)
what is the typical signalment/life style of FIC cat?
- middle aged, neutered (male/female)
- sedentary, overweight
- dry food, indoor only, litter box user
If client funds are limited, what is more important minimum database, urinalysis or CBC/chem? if you can do both, what 3rd diagnostic is also helpful?
- UA + bloodwork + plain rads (to rule out stones)
What are 3 common complaints owners report?
- (all are common LUTD signs)
if owner complains cat is inappropriately urinating and defecating, what does this likely mean is the cause?
Is the bladder painful when palpated? Is the bladder small or large?
- small (unless obstructed)
What is the most consistent finding on UA with FIC? Is pyuria a common finding? What is pH finding?
- high SG
- uncommon/not many WBCs
- pH is variable
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