patho II test 3

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tab
ID:
182147
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patho II test 3
Updated:
2012-11-06 20:11:45
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viral hepatitis
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Description:
viral hepatitis
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  1. symptoms over the past three weeks
    • tired and weak
    • appetite is good
    • sore under right ribcage (mostly when jogging)
  2. 4 occurences that could be used to rule out possible causes of the hepatitis
    • motor vehicle accident in 1996 (requiring a blood transfusion) - 1992 act to screen blood
    • cholecystitis & cholecystectomy -
    • no recent international travel
    • no unprotected sex or with anyone dx'd with viral Hep
    • drinking a 6-pack of beer on the weekend
    • large tattoos on forearms, lower legs and back
  3. functional unit of the liver
    lobule
  4. what surrounds the plates of hepatocytes
    sinusoids
  5. lobules recieve blood from where
    • portal vein
    • hepatic artery
  6. cells that are star shaped, store lipids & vitamin A, contractile and remove foreign substances from blood & trap bacteria
    lipocytes
  7. lymphatics drain lymph from where in the lobules
    disse space
  8. capillaries between plates of hepatocytes that
    drain towards the central vein
    surrounded by highly permeable endothelial cells
    lined with phagocytic Kupffer cells
    sinusoids
  9. 4 main liver functions
    • digestion
    • synthesis
    • metabolism
    • detoxification
  10. test that reflect loss of normal function
    • digestion - impaired lipid digestion
    • synthesis - loss of normal proteins
    • metabolism - drugs not metabolized
    • detoxification - inability to clear and/or conjugate drugs or endogenous factors
  11. 5 plasma chemistries and which direction they go in liver disease
    • aminotransferases (AST,ALT) increase
    • LDH - increase
    • bilirubin - increase
    • ptt - increase
    • plasma proteins, albumins,globulins decrease
  12. hepatic synthetic functions
    • fat processing
    • protein processing
    • CHO
  13. 6 hepatic metabolic functions
    • plasma proteins
    • ast
    • alt
    • ldh
    • alkaline phosphatase
    • ggt
  14. where are gamma globulins synthesized
    lymph node cells
  15. controls the flow of pancreatic juices
    sphincter of Oddi (major duodenal papilla)
  16. primary bile acids
    cholic acid & chenodeoxycholic acids
  17. process of bile secretion
    cholerisis
  18. choleretic agents/stimuli
    • high concentration of bile salts
    • secretin
  19. which hepatitis is DNA
    hep B
  20. which hep is fecal
    A & E
  21. which hep affects children and young adults
    hep A
  22. 5 stages of viral hepatitis
    • incubation
    • prodromal
    • icteric
    • recovery
    • chronic
  23. strongest risk for hep C
    IV drug use
  24. 70-90% of hep c patients develop what
    • chronic hepatitis
    • and many are at risk of cirrhosis
  25. 3 low lab values
    • vitamin A
    • albumin
    • protein, total
  26. 3 high labs
    • lymphocytes
    • monocytes
    • all liver enzymes except (unconjugated, indirect bilirubin)
  27. 2 positive lab results
    • IgG anti-HCV antibody
    • HCV RNA
  28. which lab test is a big indicator hor hep C
    HCV genotype - type 1

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