BioChem Electron transport

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BioChem Electron transport
2012-11-08 21:22:45
BioChem Electron transport

BioChem Electron transport
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  1. How is ATP synthesis accomplished?
    Oxidative Phosphorylation
  2. Where does H+ move from and into to create a proton gradient?
    moves from the inner cell membrane matrix to the interspace of the mitochondria
  3. Where do the complexes reside?
    inbedded in the inner membrane
  4. Which complexes add to the proton gradient?
    Complex 1, 3, 4
  5. How many protons cross the membrane in complex 1?
    4 H+
  6. What is the purpose of CoQ?
    Transport electrons from complex 1, 2, 3
  7. What is the term used for CoQ when it is fully oxidized and fully reduced?
    • Oxidized = Eubiquinone
    • Reduced = Eubiquinol
  8. What is the purpose of cytochromes?
    Transport electorns for complex 3 and 4
  9. Where are cytochrome C located and what do they have in the contain?
    Located on the inner membrane facing the intermembrane space and they have Iron in the middle
  10. What complex does FADH start at?
    Complex 2
  11. What complex does NADH start at?
    Complex 1
  12. How many protons are moved across the membrane at complex 3
    2 protons
  13. How many protons move across at proton 4?
    2 protons
  14. What is the main theory behind the chemiosmotic theory (Mitchell hypothesis)?
    • Proton pump
    • ATP synthase
  15. What is the purpose of glycerophosphate shuttle?
    To transfer NADH from DHAP in the cytoplasm to Glycerol-3phosphate which crossess the mitochondrial membrane converts FAD to FADH
  16. In what part of the body is glycerol-3-shuttle needed?
    Brain and Skeletal muscle
  17. What is the purpose of the malate-asperate shuttle?
    transfer NADH from OAA to malate which crosses the mictochondrial membrane then NADH into the mitochondria creating OAA which then converts to asperate in order to leave mitochondria
  18. What does it mean to say that Electron transport is tightly coupled with ATP synthesis?
    Means that one does not happen without the other
  19. What is uncoupling proteins?
    create a proton leak (brown fat) which helps heating