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topical analgesic effect to mucosal lining of urinary tract. It does not kill bacteria, it is used to control symptoms of dysuria, frequency, & urgency assoc. w/ UTI. Use it only during the 1st 24-48 hrs of antibiotic tx (will turn urine reddish orange)
- broad spectrum antibiotic bacteriostatic at common dose, bactericidal at higher dose.
- uncomplicated lower UTI
broad spectrum bactericidal agent effective v. G+ &- (UTIs)
- combo of intermediate acting sulfonamide (septra) & a synthetic anti-infective (Bactrim) effective against severely
- crystal formations in kidneys, CBC & diff, >warfarin, dilantin, oral hypoglycemics, <2 mo old
- synthetic nucleotide, interferes w/ DNA synth of Herpes I,II & zoster (inhibiting viral replication)
- nephrotox-fever chills flank p. dysuria >freq & urg.
- neuro- agitation, tremors
oseltamivir & zanamivir
- inhibits influenza A & B
- oseltamivir=oral- NV
- Zanamivir=inhalled- cough, throat irr
- take w/in 48 hrs
Flu shot contraindicators
- serious chicken allergy
- severe allergic reaction to influenza in past
- gillian bear syndrome
- moderate-severe illness w/ fever
Isoniazid + Rifampin + Pyrazinamide + Ethambutol
- four antibiotics recommended for treatment of active tuberculosis
- hepatotoxicity- ALT AST
- Ethambutol-color distortion, blurry vision
- rifampin- discolored body fluid (red, orange)
- Latent TB
- 6 mo min, 9 mo recommended
Reverse Transcriptase inhibitors
- RTIs block reverse transcriptase's enzymatic function and prevent completion of synthesis of the double-stranded viral DNA, thus preventing HIV from multiplying.
- AZT, Retrovir
- prevent viral replication by inhibiting the activity of proteases, e.g. HIV-1 protease, enzymes used by the viruses to cleave nascent proteins for final assembly of new virions.
- Most effective
- interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS
Pneumocystis Carinii Pneumonia
- fungal like organism, potentially fatal