Pharm exam 3 ID2

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Pharm exam 3 ID2
2012-11-08 22:19:01
Infectious Disease

Pharm exam 3 ID2 vocab
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  1. AZO (Phenazopyridine)
    topical analgesic effect to mucosal lining of urinary tract. It does not kill bacteria, it is used to control symptoms of dysuria, frequency, & urgency assoc. w/ UTI. Use it only during the 1st 24-48 hrs of antibiotic tx (will turn urine reddish orange)
  2. Nitrofurantoin (Macrobid)
    • broad spectrum antibiotic bacteriostatic at common dose, bactericidal at higher dose.
    • uncomplicated lower UTI
  3. Ciprofloxacin (Cipro)
    broad spectrum bactericidal agent effective v. G+ &- (UTIs)
  4. sulfamethoxazole/trimethoprim (Bactrim/Septra)
    • combo of intermediate acting sulfonamide (septra) & a synthetic anti-infective (Bactrim) effective against severely
    • crystal formations in kidneys, CBC & diff, >warfarin, dilantin, oral hypoglycemics, <2 mo old
  5. acyclovir (Zovirax)
    • synthetic nucleotide, interferes w/ DNA synth of Herpes I,II & zoster (inhibiting viral replication)
    • nephrotox-fever chills flank p. dysuria >freq & urg.
    • neuro- agitation, tremors
  6. oseltamivir & zanamivir
    • inhibits influenza A & B
    • oseltamivir=oral- NV
    • Zanamivir=inhalled- cough, throat irr
    • take w/in 48 hrs
  7. Flu shot contraindicators
    • serious chicken allergy
    • severe allergic reaction to influenza in past
    • gillian bear syndrome
    • moderate-severe illness w/ fever
  8. Isoniazid + Rifampin + Pyrazinamide + Ethambutol
    • four antibiotics recommended for treatment of active tuberculosis
    • hepatotoxicity- ALT AST
    • Ethambutol-color distortion, blurry vision
    • rifampin- discolored body fluid (red, orange)
  9. Isoniazid
    • Latent TB
    • 6 mo min, 9 mo recommended
  10. Reverse Transcriptase inhibitors
    • RTIs block reverse transcriptase's enzymatic function and prevent completion of synthesis of the double-stranded viral DNA, thus preventing HIV from multiplying.
    • AZT, Retrovir
  11. Protease Inhibitors
    • prevent viral replication by inhibiting the activity of proteases, e.g. HIV-1 protease, enzymes used by the viruses to cleave nascent proteins for final assembly of new virions.
    • Most effective
    • Kaletra
  12. Fusion Inhibitors
    • interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS
    • Fuzeon
  13. Pneumocystis Carinii Pneumonia
    • fungal like organism, potentially fatal
    • tx=Bactrim