NCTI- Pharmacology- Drug List J- Haloperidol

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RunNickMarini
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18306
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NCTI- Pharmacology- Drug List J- Haloperidol
Updated:
2010-05-08 12:14:16
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NCTI Pharmacology Drug List Haloperidol
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NCTI- Pharmacology- Drug List J- Haloperidol
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  1. Haloperidol
    class
    Haldol
  2. Haloperidol
    trade name
    • antipsychotic
    • tranquilizer
  3. Haloperidol
    mechanism of action
    • 1. demonstrates anti-psychotic effects by blocking dopamine receptors in the brain (dopamine receptors are linked to mood and behavior)
    • 2. exerts strong anti-emetic effects and impairs central thermoregulation
  4. Haloperidol
    indications
    • 1. acute psychotic disorders/episodes
    • 2. delirium
  5. Haloperidol
    contraindications
    • 1. Parkinson’s Disease
    • 2. seizure disorders
    • 3. coma
    • 4. alcoholism
    • 5. ALOC
    • 6. Safe use during pregnancy, in nursing mothers, and in children < 3 years has not been established
  6. Haloperidol
    side effects
    • CNS: Extrapyramidal reactions, dystonia, restlessness, reflexive anxiety, Combativeness (particularly in elderly patient administration)
    • Cardiovascular: tachycardia, hypotension, ECG changes
    • GI: dry mouth, constipation, diarrhea, N/V
    • Respiratory: respiratory depression, bronchospasm
  7. Haloperidol
    notes
  8. Haloperidol
    precautions
    Use with caution in elderly or debilitated patients or those with severe Cardiovascular disorders.
  9. Haloperidol
    interactions
    CNS depressants, opiates and alcohol may increase CNS depression, may also antagonize oral anti-coagulants
  10. Haloperidol
    routes
    IM, PO (in inpatient care settings)
  11. Haloperidol
    onset and duration
    Onset in 10-45 minutes; peak effect in 10-20 min, can last up to 36 hours.
  12. Haloperidol
    dosage
    • Adult: 2-5 mg IM
    • Pediatric: 0.05-0.15 mg/kg/day PO typically divided into 2 or 3 doses

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