STATINS - DR. DAVIS

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davis.tiff
ID:
183603
Filename:
STATINS - DR. DAVIS
Updated:
2012-11-17 10:37:25
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PHARMACOLOGY
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Description:
PHARM EXAM III
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  1. True or false. The higher the risk, the lower the LDL target level.
    true
  2. Which of the following describes the mechanism of action for cholestyramine and colestipol?

    A. activates GPCR in adipose and decreases the release of fatty acids from stored triglycerides
    B. activates PPAR-alpha
    C. inhibition of HMG-CoA reductase
    D. tightly bind to bile acids
    D. tightly bind to bile acids
    (this multiple choice question has been scrambled)
  3. A 35 year-old woman presents with significantly elevated LDL, elevated triglycerides and lowered HDL levels. She has a history of liver disease and is currently taking OTC Pepcid for indigestion. Which of the following would be the best treatment option for her?

    a. pravastatin + niacin
    b. simvastatin + niacin
    d. simvastatin + cholestyramine
    e. simvastatin only
    d. simvastatin + cholestyramine
  4. You recently prescribed pravastatin for one of your patients with hyperlipidemia. All of the following are possible side effects that you might see in this patient EXCEPT:

    A. myopathy
    B. all of the following are possible side effects
    C. rhabdomyolysis
    D. decreased vitamin D synthesis
    E. decreased HDL
    E. decreased HDL
    (this multiple choice question has been scrambled)
  5. Activation of PPAR-alpha and a reduction in the release of VLDL from the liver is a mechanism of action descriptive of:

    A. niacin
    B. fibrates
    C. pravastatin
    D. simvastatin
    E. bile-acid resins
    B. fibrates
    (this multiple choice question has been scrambled)

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