DIABETIC DRUGS - DR. DAVIS

A 37 year-old obese woman comes into your office with complaints of uncontrolled blood sugar over the last few months. The onset of her diabetes is recent and is most likely due to insulin resistance and obesity. She does not have a history of renal or liver disease. Which of the following would be the drug of choice for treating her type-2 diabetes mellitus?

A. sitagliptin
B. rosiglitazone
C. exenatide
D. metformin
E. glipizide

All of the following are possible side effects of sulfonylureases EXCEPT:

A. hypoglycemia
B. mental confusion
C. weight loss
D. tremors
E. blurred vision

Which of the following mechanisms of action is descriptive of insulin?

A. agonistic binding to PPAR-gamma and suppression of resistin release from adipocytes
B. activation of AMP kinase
C. binding to tyrosine kinase receptor and activating downstream signaling and second messenger cascade
D. stimulates release of more insulin from beta-cells of pancreas
e. none of the above are descriptive of the mechanism of action for insulin

True or false. Insulin should only be used to treat T1DM.

Which of the following is the drug of choice for insulin resistance and is typically used as a combination therapy with metformin, sulfonylurea and/or insulin?

A. pioglitazone
B. repaglinide
C. exenatide
D. sitagliptin
E. glucagon

Which of the following is the most likely to cause hypoglycemia as a side effect?

A. pioglitazone
B. exenatide
C. insulin
D. glucagon
E. nateglinide

Which of the following would be the best treatment for diabetic coma caused by an  insulin overdose?

A. sitagliptin
B. glucagon
C. metformin
D. acarbose
E. exenatide