Biomed module 8 obj. 1-4
Card Set Information
Biomed module 8 obj. 1-4
Biomed module obj
Biomed module 8 obj.1-4
The surface of the _______ is about ___m2 in an adult. It weighs about ______, more than twice as much as any other ______ and about ____of body weight.
skin, 2, 5kg, organ, 1/6
The skin is also called _______ and _________.
dermis and epidermis
The branch of medicine that treats diseases of the skin.
Why is the dermatological disease
In this disease the patiant mounts an immune defense (autoimmunity) against proteins of his own desmosomes and hemidesmosomes.
Which cell junctions are are critical for skin structure and function?
Outside layer of the skin
mostly comprised of dead cells, which have expelled their nucleus and all organelles
become simply bags of a protien called
A living layer of tissue undrneath the
contains that blood vessels, nervers , glands, and living skin cells
Hair roots are found in the dermis , and there is a small bit of muscle (the
) wich controls the angle of each hair.
beneath the dermis
Also called the
Not technichally part of the skin, but is a layer of areolar and/or adipose connective tissue.
What are the 3 layers of the Integument (Skin) structure?
Superficial to deep
3. Subcutaneous (hypodermis) layer
The skin is...
keratinized statified squamous epithelium
What are the layeres of the Epidermis from
: lay rom which all others regenerate
A mnemonic for these layers is -
Another mnemonic from
all layers of the dermis contain Keratinocytes
generated by cell division in the
(deepest layer of epidermis).
the more superficial the layer the more dead keratinocytes predominate
The ______ _______ consist entirely of two dozen rows of deat, flat ___________ with no other cell types present.
stratum corneum, keratinocytes
True or false: The other cell types (other than
s) are found only in the deeper layers of the epidermis : basale and spinosum.
...only in thick (hairless) skin.
Keratinocytes are constanly made in the _______ _______ and as cells are pushed more _________, they lose their ______ and _______ and become dead bags of ________.
stratum basale, superfically, nucleus, organells, keratin
these cells are also called
, and they are constanly shed from the surface of the
The shed fakes are called
Humans shed about ________ dead keratinocytes per hour. These dead ____ ____ amount to about _______ per day or _______ per year.
600,000, skin cells, 2grams, 0.7 kg
True ore false: And estimated 1/3 orm more of "housedust" is shed skin flakes. (Only about half is soil from the outdoors. The remainer is carpet and upholstery fibers.)
When someone is allergic to "house dust" they are actually allergic to ...
...dust mite dung
, eats skin flakes as its primary source of food. Its feces are a strong allergen for many humans.
What are the two types of skin?
Thin and thick
covers everthing except th palms, fingertips, and soles of the feet
is about 0.1mm thick
are very thin
also called glabrous (latin glaber, "bald") skin
found on the ventral (palmer) surface of the hand (i.e. palms and fingertips) and on the soles (plantar surface) of the feet.
from 6 to 45 times as thick as thin skin
most of the increased thickness is because of the
spinosum, lucidum, and corneum.
What are the four cell types found in the epidermins?
a cell membrane surrounding the protein
Makes up about 90% of the cells of the epidermis
These also secrete lipids that give skin waterproof and flexible properties.
About 8% of the cells in the epidermis
, pigment granuels that give the skin its color
the skins version of a type of immune cell calleda dendritic cell
Donot confuse these with the beta cells of the islets of langerhans in the pancreas
: same name, completely different function
The rarest epidermal cell
A type of nervous system cell that detects light touch.
The ____ is specialized to protect the _____ and to ______ against microbial ________.
skin, body, defend, invaders
The skin serves to _____ the blood, when necessay, and to _____ the sensory modalties of _____: pressure, _______, pain, ________.
cool, detect, touch, vibration, temperature
Keratin and lipids of the skin...
...help make a waterproof seal between the moist tissues below and the dry outside world.
There is a small amount of ________ from the skin. The skin also is critical in the _________ of precursors which form ___________.
excretion, activation, vitamin D