NCTI- Pharmacology- Drug List A- Morphine Sulfate

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RunNickMarini
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18389
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NCTI- Pharmacology- Drug List A- Morphine Sulfate
Updated:
2010-05-08 22:29:44
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NCTI Pharmacology Drug List Morphine Sulfate
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NCTI- Pharmacology- Drug List A- Morphine Sulfate
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  1. Morphine Sulfate
    trade name
    none
  2. Morphine Sulfate
    class
    • opioid narcotic
    • CNS depressant
  3. Morphine Sulfate
    mechanism of action
    • 1. Alters pain perception and produces euphoria
    • 2. Decreases myocardial oxygen demand by decreasing preload (venous pooling due to peripheral vasodilation) and decreasing afterload (decreased systemic vascular resistance due to peripheral vasodilation)
    • 3. Depresses the CNS by interacting with opiate receptors in the brain
  4. Morphine Sulfate
    indications
    • Moderate to severe pain
    • Chest pain of suspected myocardial origin
    • Pulmonary Edema from Congestive Heart Failure with or without chest pain
    • Burns
  5. Morphine Sulfate
    contraindications
    • Altered level of consciousness
    • Abdominal pain of unknown etiology
    • Respiratory depression
    • Head injury
    • Hypovolemia
  6. Morphine Sulfate
    side effects
    • Cardiovascular: bradycardia, hypotension, (rebound tachycardia/hypertension)
    • Neurological: sedation, agitation, tremors/seizures, hallucinations
    • Respiratory: depression, arrest
    • Gastrointestinal: nausea/vomiting
  7. Morphine Sulfate
    precautions
    Morphine Sulfate is an opiate derivative – Naloxone should be available to reverse any severe respiratory side effects
  8. Morphine Sulfate
    interactions
    Use with caution with patients taking other analgesics, depressants or narcotics
  9. Morphine Sulfate
    routes
    IV, IO, IM
  10. Morphine Sulfate
    onset
    IV/IO will have an onset of 2-5 minutes and IM will have an onset of 5-10 minutes. Each will last approximately 3-5 hours
  11. Morphine Sulfate
    dosages
    • Adult:
    • Pain Relief: 1.0 – 10.0 mg IV titrated to pain relief or 5.0 – 10.0 mg IM as a single dose only
    • Pulmonary Edema: 5.0 – 10.0 mg slow IV push (2.0 mg/minute)

    Pediatric: 0.1 – 0.2 mg/kg slow IV push (1.0 mg/minute) titrated to pain relief or 0.1 mg/kg IM
  12. Morphine Sulfate
    notes
    May draw 10 mg (1 ml) into a 10 ml syringe and mix with 9 ml of Normal Saline. This creates a 1 mg/1 ml concentration for better control when administering the medication.

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